Infencia Xavier Raj

Program: Cancer Biology

Current advisor: Grant Challen, PhD

Undergraduate university: Anna University, 2016

Enrollment year: 2021

Research summary
Understanding the molecular mechanism of Dnmt3a-mediated DNA methylation in HSC and Leukemia.

Graduate publications
Xavier Raj I, Kyun Koh W, Harrison J, Zhang CR, Soares B, Amato R, Krishnan A, O’Leary DR, Bjeije H, Parsons TM, Han W, Young AL, Wang T, Batista LFZ, Challen GA. 2025 Non-canonical functions of DNMT3A in hematopoietic stem cells regulate telomerase activity and genome integrity. Cell Stem Cell, 32(8):1251-1266.e8. PMCID: PMC12313198

Dunuwille W, Wilson WC, Bjeije H, IssaN, Han W, Parsons TM, Young AL, Raj IX, Krsihnan A, Gaur T, Wang ES, Weng AP, Stubbs MC, Celik H, Cashen AF, Edwards JR, Challen GA. 2024 BIRC5 upregulation enhances DNMT3A-mutant T-ALL cell survival and pathogenesis. Blood Neoplasia, 1(4):100040. PMCID: PMC12182843