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Nada A. Abumrad, Ph.D.
- Fatty acids regulate energy balance and tissue renewal. Dysfunction of this regulation causes disease
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Jennifer Alexander-Brett, M.D., Ph.D.
- Respiratory immunobiology, with particular interest in cytokine pathways associated with lung epithelial progenitors
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Ream Al-Hasani, Ph.D.
- Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.
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Gaya K. Amarasinghe, Ph.D.
- Molecular mechanisms at the host-pathogen interface
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Maxim Artyomov, Ph.D.
- Systems immunology using high-throughput next-generation sequencing in conjunction with mathematical and statistical modeling approaches rooted in statistical physics
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Monika Bambouskova, Ph.D.
- Immunometabolism - metabolic regulation of immune cell activation
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Thomas J. Baranski, M.D., Ph.D.
- Signal transduction by G proteins and pathogenesis of diabetes
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David L. Bark, Ph.D.
- Applying biomechanics and mechanobiology (the interaction and response of cells and tissue to mechanical forces) to diagnose, study, and treat various forms of cardiovascular disease.
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Wayne M. Barnes, Ph.D.
- Inventing a new way to sequence DNA; PCR at one temp; RT-enabled Taq pol.
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Philip V. Bayly, Ph.D.
- The application of nonlinear dynamics and vibrations to mechanical and biomedical systems
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Mikhail Berezin, Ph.D.
- Investigation the mechanism of peripheral neuropathies
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Matthew R. Bersi, Ph.D.
- Our research is focused on soft tissue biomechanics and mechanobiology
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Joshua Blodgett, Ph.D.
- Interdisciplinary questions surrounding bacterial small molecule production
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Kendall J. Blumer, Ph.D.
- Tumor cell biology, signal transduction, and drug development
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Irving Boime, Ph.D.
- Placental and pituitary hormone genes
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Ron Bose, M.D., Ph.D.
- Genomics and Cell Signaling in Breast Cancer
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Thomas J. Brett, Ph.D.
- The molecular basis of lung diseases and drug development using structural biology tools
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Peter M.J. Burgers, Ph.D.
- Molecular Biology of DNA replication and damage response in yeast and human
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Michael G. Caparon, Jr, Ph.D.
- Genetics and virulence of the pathogenetic streptococci
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Anders E. Carlsson, Ph.D.
- Simulation and theory of force generation by actin polymerization
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Valeria Cavalli, Ph.D.
- Cellular, Molecular and Epigenetic control of axon regeneration
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Baron Chanda, Ph.D.
- Mechanisms and Design Principles of Ion Channel Function and Gating
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Tao Che, Ph.D.
- Characterizing and dissecting the molecular mechanisms of opioid receptor signaling
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Yao Chen, Ph.D.
- Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals
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Ying Maggie Chen, M.D., Ph.D.
- Understanding the molecular mechanisms of primary nephrotic syndrome (NS)
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Zhou-Feng Chen, Ph.D.
- Molecular and cellular mechanisms of itch sensation
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Wayland W. L. Cheng, M.D., Ph.D.
- I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.
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ShiNung Ching, Ph.D.
- The interface between systems and control engineering, neuroscience and neural medicine
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Jaehyung (Gus) Cho, Ph.D.
- Understanding the mechanism mediating intravascular cell-cell interactions and vascular occlusion under thromboinflammatory conditions, including thrombosis, ischemia/reperfusion injury, and sickle cell disease
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Bryan Copits, Ph.D.
- How different types of neurons encoding somatosensory modalities are assembled into functional circuits
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Clair Crewe, Ph.D.
- Understanding extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation
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Erika C. Crouch, Ph.D., M.D.
- Structure and function of surfactant protein D (SP-D)
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Jianmin Cui, Ph.D.
- Molecular basis of bioelectricity and related diseases in nervous and cardiovascular systems; ion channel function and modulation; discovery of drugs that target ion channels
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Nicholas O. Davidson, M.D.
- Mammalian gene expression: Regulation through mRNA editing and RNA stabilization
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Gus Davis, M.D., Ph.D.
- Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
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Ram Dixit, Ph.D.
- Molecular mechanisms of cytoskeleton organization and function
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Sergej Djuranovic, Ph.D.
- Molecular mechanisms of translational control
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Tamara L. Doering, M.D., Ph.D.
- Biology and pathogenesis of the pathogenic fungus Cryptococcus neoformans
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Adam T. Eggebrecht, Ph.D.
- Developing novel tools that extend mapping of brain function beyond current limitations
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Bahaa E. Elgendy, Ph.D.
- Medicinal chemistry with a broad goal of drug design and organic synthesis
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Elliot L. Elson, Ph.D.
- Mechanical properties of reconstituted tissues; fluctuation spectroscopy of protein interactions
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Alex S. Evers, M.D.
- Molecular mechanisms of anesthetic action - Proteomics of GABAA receptors
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Daved H. Fremont, Ph.D.
- Mechanisms of host immunity and viral evasion
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Eric A. Galburt, Ph.D.
- Biophysical studies of transcription initiation in Eukaryotes and Mycobacterial tuberculosis
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Roberto Galletto, Ph.D.
- Mechanistic studies of DNA motor proteins; single Molecule Biochemistry
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Guy M. Genin, Ph.D.
- Interfaces and adhesions in physiology and nature
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Daniel E. Goldberg, M.D., Ph.D.
- Biochemistry of malaria
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Dennis Goldfarb, Ph.D.
- Computational mass spectrometry, proteomics, and their applications in biology
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Gregory A. Grant, Ph.D.
- Relationship of structure to function in allosteric control mechanisms
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Michael J. Greenberg, Ph.D.
- The Greenberg lab seeks to understand the molecular and cellular biophysics of heart disease, with the goal of engineering disease models and precision therapeutics
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Michael L. Gross, Ph.D.
- Development and application of mass spectrometry in biophysics, biochemistry, and medicine
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Richard W. Gross, M.D., Ph.D.
- The molecular mechanisms through which biologic membranes participate in cellular activation processes
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Kathleen B. Hall, Ph.D.
- We study RNA folding and RNA binding to proteins
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Jeffrey Haspel, M.D., Ph.D.
- Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease
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Jen M. Heemstra, Ph.D.
- Utilization of nucleic acid molecular recognition and self-assembly to generate functional architectures for biosensing and bioimaging
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Jason M. Held, Ph.D.
- Redox biochemistry in cell signaling and disease, Proteomics
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Jeffrey P. Henderson, M.D., Ph.D.
- Biochemical interactions between humans and bacteria in health and disease
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Alex Holehouse, Ph.D.
- Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
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James E. Huettner, Ph.D.
- Glutamate receptors, synaptic transmission and stem cell differentiation
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Scott J. Hultgren, Ph.D.
- Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.
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Joseph Ippolito, M.D., Ph.D.
- Precision medicine through metabolism-based imaging and therapy: from laboratory to clinical translation
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Meredith E. Jackrel, Ph.D.
- Protein folding and misfolding, and the engineering and application of protein disaggregases to reverse misfolding
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James W. Janetka, Ph.D.
- The rational structure-based drug design and synthesis for cancer and infectious disease
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Silvia Jansen, Ph.D.
- we study the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions including cell migration, intracellular trafficking and cytokinesis.
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Joseph Jez, Ph.D.
- Exploring regulatory networks in metabolism - structural biology and biochemistry of plants and microbes
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Tao Ju, Ph.D.
- Developing geometric algorithms for interpreting protein structures from low-resolution density maps produced by cryo-electron microscopy and X-ray crystallography
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David Kast, Ph.D.
- Understand fundamental cellular and molecular mechanisms that drive the biogenesis and dynamics of intracellular membrane compartments
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Dineo Khabele, M.D.
- clinical and translational research in gynecologic oncology, with a focus on ovarian cancer
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S. Kerry Kornfeld, M.D., Ph.D.
- organismal aging; zinc homeostasis and roles of zinc during cell differentiation.
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Sándor J. Kovács, Ph.D., M.D.
- Quantitative cardiovascular physiology, mathematical modeling of systems physiology, imaging
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Albert M. Lai, Ph.D.
- My research is in clinical research informatics, but I also have strong interest in other areas of clinical informatics, including usability of clinical and consumer-facing systems and mobile health
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Gregory M. Lanza, M.D., Ph.D.
- Noninvasive molecular imaging and drug delivery research
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Daisy W. Leung, Ph.D.
- Defining molecular mechanisms at the host-pathogen interface
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Petra Anne Levin, Ph.D.
- Bacterial growth and antibiotic susceptibility
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Matthew D. Lew, Ph.D.
- Developing novel optical tools for biology and medicine
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Jr-Shin Li, Ph.D.
- Control and optimization of large-scale complex systems with applications ranging from quantum mechanics and neuroscience to bioinformatics
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Weikai Li , Ph.D.
- Membrane protein structure and function
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Christopher J. Lingle, Ph.D.
- Structure-function studies of Slo family K+ channels
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Timothy M. Lohman, Ph.D.
- Mechanisms of DNA helicases/translocases and SSB proteins
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Nupam P. Mahajan, Ph.D.
- How tyrosine phosphorylation regulates epigenetic processes that affect cellular homeostasis and cancer cell survival
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Moe Mahjoub, Ph.D.
- The microtubule cytoskeleton in health and disease
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Ben Major, Ph.D.
- Studying how perturbation of specific signal transduction pathways contributes to the initiation, progression and dissemination of cancer
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Susruta Majumdar, Ph.D.
- Research in the laboratory is aimed at attaining functional selectivity of opioid agonist action from its own target adverse effects while integrating chemical synthesis with biochemical, genetic and pharmacological approaches.
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Jordan G. McCall, Ph.D.
- Understanding the neural mechanisms underlying emotional dysregulation in the contexts of stress, chronic pain, and addiction
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William H. McCoy, M.D., Ph.D.
- We investigate how host-microbe interactions at epithelial barrier sites impact skin diseases
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Mark Meacham, Ph.D.
- Studies microfluidics, micro-electromechanical systems and associated transport phenomena
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Robert W. Mercer, Ph.D.
- Molecular and cell biology of ion pumps and transporters in plasma membrane; cell polarity
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Timothy M. Miller, M.D., Ph.D.
- Mechanisms of neurodegeneration and targeted therapies for neurodegenerative diseases
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Liviu M. Mirica, Ph.D.
- Development of specific inhibitors of histone demethylases; design of therapeutic and imaging chemical agents for Alzheimer's disease
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Makedonka Mitreva, Ph.D.
- Next-generation genomic and computational approaches to empower the study of infectious diseases and the human microbiome
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Kevin D. Moeller, Ph.D.
- Developing new methods for peptide mimetic, natural product synthesis, and the construction of addressable molecular arrays
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Tae Seok Moon, Ph.D.
- Building the Future with Synthetic Biology
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Jose A. Moron-Concepcion, Ph.D.
- Elucidating the molecular mechanisms underlying opiate dependence
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Nima Mosammaparast, M.D., Ph.D.
- Understanding the molecular mechanisms of the DNA damage response and DNA repair in human cells
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Colin G. Nichols, Ph.D.
- Ion channel biology in health and disease
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Natalie M. Niemi, Ph.D
- Understanding how mitochondria are built, regulated, and maintained
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Dmitri A. Nusinow, Ph.D.
- Circadian clock regulation of physiology and development in plants.
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Dave Pagliarini, Ph.D.
- We seek to understand the cellular and biochemical underpinnings of mitochondrial dysfunction in human diseases. Our work integrates large-scale methodologies with traditional biochemistry and cell biology to investigate the modulation, adaptation, and basic metabolic function of mitochondria.
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Himadri B. Pakrasi, Ph.D.
- Systems and Synthetic Biology of photosynthetic organisms
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Rohit V. Pappu, Ph.D.
- Biophysics of intrinsically disordered proteins
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