Crystal Song

Program: Molecular Cell Biology

Current advisor: David M. Holtzman, MD

Undergraduate university: University of California-Los Angeles, 2020

Enrollment year: 2021

Research summary
Development of novel therapies for Alzheimer’s Disease

Graduate publications
Parhizkar S, Bao X, Chen W, Rensing N, Chen Y, Kipnis M, Song S, Gent G, Tycksen E, Manis M, Lee C, Serrano JR, Bosch ME, Franke E, Yuede CM, Landsness EC, Wong M, Holtzman DM. 2025 Lemborexant ameliorates tau-mediated sleep loss and neurodegeneration in males in a mouse model of tauopathy. Nat Neurosci, 28(7):1460-72. PMCID: PMC12277058

Chen Y, Song S, Parhizkar S, Lord J, Zhu Y, Strickland MR, Wang C, Park J, Tabor GT, Jiang H, Li K, Davis AA, Yuede CM, Colonna M, Ulrich JD, Holtzman DM. 2024 APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread. Cell, 187(2):428-445.e20. PMCID: PMC10842861