Hannah Edwards

Program: Neurosciences

Current advisor: John R. Cirrito, PhD

Undergraduate university: University of Colorado-Boulder, 2015

Enrollment year: 2019

Research summary

Using in vivo microdialysis to examine the changes to interstitial amyloid beta and tau due to stress and sex hormone interactions in awake and behaving animals.

Graduate publications
Edwards HM, Wallace CE, Gardiner WD, Doherty BM, Harrigan RT, Yuede KM, Yuede CM, Cirrito JR. 2023 Sex-dependent effects of acute stress on amyloid-β in male and female mice. Brain, 146(6):2268-74. PMCID: PMC10232275

Izzo NJ, Yuede CM, LaBarbera KM, Limegrover CS, Rehak C, Yurko R, Waybright L, Look G, Rishton G, Safferstein H, Hamby ME, Williams C, Sadlek K, Edwards HM, Davis CS, Grundman M, Schneider LS, DeKosky ST, Chelsky D, Pike I, Henstridge C, Blennow K, Zetterberg H, LeVine H 3rd, Spires-Jones TL, Cirrito JR, Catalano SM. 2021 Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer’s disease modification. Alzheimers Dement, 17(8):1365-82

Yuede CM, Wallace CE, Davis TA, Gardiner WD, Hettinger JC, Edwards HM, Hendrix RD, Doherty BM, Yuede KM, Burstein ES, Cirrito JR. 2021 Pimavanserin, a 5HT 2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease. J Neurochem, 156(5):658-73. PMCID: PMC7946332

Yuede CM, Timson BF, Hettinger JC, Yuede KM, Edwards HM, Lawson JE, Zimmerman SD, Cirrito JR. 2018 Interactions between stress and physical activity on Alzheimer’s disease pathology. Neurobiol Stress, 8():158-71