Jackie Garcia

Program: Biochemistry Biophysics and Structural Biology

Current advisor: Farshid Guilak, PhD

Undergraduate university: University of Nebraska-Lincoln, 2017

Enrollment year: 2018

Research summary
Mechanotransduction via Piezo1 channels in chrondrocytes

Graduate publications
Savadipour A, Nims RJ, Rashidi N, Garcia-Castorena JM, Tang R, Marushack GK, Oswald SJ, Liedtke WB, Guilak F. 2023 Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes. Proc Natl Acad Sci USA, 120(30):e2221958120. PMCID: PMC10372640

Ezekian JE, Clippinger SR, Garcia JM, Yang Q, Denfield S, Jeewa A, Dreyer WJ, Zou W, Fan Y, Allen HD, Kim JJ, Greenberg MJ, Landstrom AP. 2020 Variant R94C in TNNT2-Encoded Troponin T Predisposes to Pediatric Restrictive Cardiomyopathy and Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction. J Am Heart Assoc, 9(5):e015111. PMCID: