Jiameng Sun

Program: Developmental Regenerative and Stem Cell Biology

Current advisor: Brian J. DeBosch, MD, PhD

Undergraduate university: University of Wisconsin-Madison, 2020

Enrollment year: 2020

Research summary

My thesis research focuses on studying the metabolic function of a canonical circadian gene Period 1 in hepatocytes under different diet conditions.

Graduate publications
Zhang Y, Sun J, Wasserman HD, Adams JA, Higgins CB, Kelly SC, Lantier L, DeBosch BJ. 2024 A Structure-function Analysis of Hepatocyte Arginase 2 Reveals Mitochondrial Ureahydrolysis as a Determinant of Glucose Oxidation. Cell Mol Gastroenterol Hepatol, 17(5):801-20. PMCID: PMC10966292

Maestas MM, Ishahak M, Augsornworawat P, Veronese-Paniagua DA, Maxwell KG, Velazco-Cruz L, Marquez E, Sun J, Shunkarova M, Gale SE, Urano F, Millman JR. 2024 Identification of unique cell type responses in pancreatic islets to stress. Nat Commun, 15(1):5567. PMCID:

Higgins CB, Adams JA, Ward MH, Greenberg ZJ, Milewska M, Sun J, Zhang Y, Chiquetto Paracatu L, Dong Q, Ballentine S, Li W, Wandzik I, Schuettpelz LG, DeBosch BJ. 2023 The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes. J Biol Chem, 299(2):102835. PMCID: PMC9900517