John Wildenthal

Program: Computational and Systems Biology

Current advisor: Jeffrey P. Henderson, MD, PhD

Undergraduate university: Ohio State University-Columbus, 2018

Enrollment year: 2019

Research summary
Metabolomic analysis of surgical site infections

I am in the lab of Dr. Jeffrey Henderson, studying surgical site infections. We are currently using metabolomic techniques to (1) look for early biomarkers of infection, before clinical symptoms are present (2) determine ways that bacteria interact with the host and each other during infections and co-infections using metabolites and their alterations.

Graduate publications
Heffernan JR, Wildenthal JA, Tran H, Katumba GL, McCoy WH, Henderson JP. 2024 Yersiniabactin is a quorum-sensing autoinducer and. mBio, 15(2)::e0027723. PMCID: PMC10865836

Wildenthal JA, Schwartz DJ, Nolan NS, Zhao L, Robinson JI, Jones E, Jawa R, Henderson JP, Marks LR. 2023 Everything but the Kitchen Sink: An Analysis of Bacterial and Chemical Contaminants Found in Syringe Residue From People Who Inject Drugs. Open Forum Infect Dis, 11(1)::ofad628. PMCID: PMC10766411

Zou Z, Potter RF, McCoy WH 4th, Wildenthal JA, Katumba GL, Mucha PJ, Dantas G, Henderson JP. 2023 E. coli catheter-associated urinary tract infections are associated with distinctive virulence and biofilm gene determinants. JCI Insight, 8(2):e161461. PMCID: PMC9977300

Wildenthal JA, Atkinson A, Lewis S, Sayood S, Nolan NS, Cabrera NL, Marschall J, Durkin MJ, Marks LR. 2022 Outcomes of Partial Oral Antibiotic Treatment for Complicated S. aureus Bacteremia in People Who Inject Drugs. Clin Infect Dis, ciac714(epub ahead of print):. PMCID:

Marks LR, Calix JJ, Wildenthal JA, Wallace MA, Sawhney SS, Ransom EM, Durkin MJ, Henderson JP, Burnham CD, Dantas G. 2021 Staphylococcus aureus injection drug use-associated bloodstream infections are propagated by community outbreaks of diverse lineages. Commun Med (Lond), 1():52. PMCID: PMC9053277