Kevin Yin

MSTP in PhD Training

Program: Developmental Regenerative and Stem Cell Biology

Current advisor: Timothy J. Ley, MD

Undergraduate university: Washington University, 2019

Enrollment year: 2020

Research summary
The role of immune escape in Acute Myeloid Leukemia progression

We are investigating whether Acute Myeloid Leukemia (AML) with different initiating and cooperating mutations lead to different immune responses, and whether there are common and unique mechanisms of immune escape. A better understanding of the mechanisms of immune escape in AML can lead to rational design of novel immunotherapies for AML.

Graduate publications
Li G, Brumback BD, Huang L, Zhang DM, Yin T, Lipovsky CE, Hicks SC, Jimenez J, Boyle PM, Rentschler SL. 2022 Acute Glycogen Synthase Kinase-3 Inhibition Modulates Human Cardiac Conduction. JACC Basic Transl Sci, 7(10):1001-17. PMCID: PMC9626903