Mandy Chan

Program: Immunology

Current advisor: Joel Schilling, MD, PhD

Undergraduate university: Emory University, 2018

Enrollment year: 2018

Research summary
Interplay between Kupffer Cell Fatty Acid Metabolism and Effector Functions in Non-Alcoholic Fatty Liver Disease

Graduate publications
Borcherding N, Jia W, Giwa R, Field RL, Moley JR, Kopecky BJ, Chan MM, Yang BQ, Sabio JM, Walker EC, Osorio O, Bredemeyer AL, Pietka T, Alexander-Brett J, Morley SC, Artyomov MN, Abumrad NA, Schilling J, Lavine K, Crewe C, Brestoff JR. 2022 Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood. Cell Metab, 34(10):1499-1513. PMCID: PMC9547954

Daemen S, Gainullina A, Kalugotla G, He L, Chan MM, Beals JW, Liss KH, Klein S, Feldstein AE, Finck BN, Artyomov MN, Schilling JD. 2021 Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH. Cell Rep, 34(2):108626. PMCID: PMC7877246

Daemen S, Chan MM, Schilling JD.. 2021 Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH. STAR Protocols, 2(2):100511. PMCID: PMC8102804