Michael Moore

Program: Molecular Genetics and Genomics

Current advisor: Ting Wang, PhD

Undergraduate university: Washington University, 2021

Enrollment year: 2021

Research summary
Molecular mechanisms determining head and neck cancer progression and treatment response

Co-mentored by the Wang and Puram labs, my work focusing on identifying molecular and epigenetic mechanisms underlying head and neck cancer progression and treatment response. I am interested in the role of transposable elements in HNSCC, differential mechanisms across HNSCC subtypes, and factors governing response to treatment (eg. chemotherapy, radiation, immunotherapy) focusing on mechanisms by which tumor sub-populations evade treatment.

Graduate publications
Jang HJ#, Shah NM#, Maeng JH#, Liang Y#, Basri NL. Ge J, Qu X, Mahlokozera T, Tzeng SC, Williams RB, Moore MJ, Annamalai D, Chen JY, Lee HJ, DeSouza PA, Li D, Xing X, Kim AH, Wang T. 2024 Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells. Nat Genet, 56(9):1903-13. PMCID: