Omar Osorio

Program: Immunology

Current advisor: Jennifer Alexander-Brett, MD, PhD

Undergraduate university: Northwest University, 2017

Enrollment year: 2019

Research summary
Extracellular Vesicle mediated Non-classical Cytokine Secretion

Graduate publications
Raphael HE, Hassan GF, Osorio OA, Cohen LS, Payne MD, Katz-Kiriakos E, Tata I, Hicks J, Byers DE, Zhang B, Alexander-Brett J. 2024 Activator protein transcription factors coordinate human IL-33 expression from noncanonical promoters in chronic airway disease. JCI Insight, 9(5)::e174786. PMCID: PMC10972587

Barlin M, Erdmann-Gilmore P, Mudd JL, Zhang Q, Seymour RW, Guo Z, Miessner JR, Goedegebuure SP, Bi Y, Osorio OA, Alexander-Brett J, Li S, Ma CX, Fields RC, Townsend RR, Held JM. 2023 Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin. Mol Cell Proteomics, 22(1):100476. PMCID: PMC9801135

Katz-Kiriakos E, Steinberg DF, Kluender CE, Osorio OA, Newsom-Stewart C, Baronia A, Byers DE, Holtzman MJ, Katafiasz D, Bailey KL, Brody SL, Miller MJ, Alexander-Brett J. 2022 Epithelial IL-33 appropriates exosome trafficking for secretion in chronic airway disease. JCI Insight, 6(4):e136166. PMCID: PMC7934940

Borcherding N, Jia W, Giwa R, Field RL, Moley JR, Kopecky BJ, Chan MM, Yang BQ, Sabio JM, Walker EC, Osorio O, Bredemeyer AL, Pietka T, Alexander-Brett J, Morley SC, Artyomov MN, Abumrad NA, Schilling J, Lavine K, Crewe C, Brestoff JR. 2022 Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood. Cell Metab, 34(10):1499-1513. PMCID: PMC9547954