People

Program: Molecular Genetics and Genomics

Graduation Year: 2008

Thesis Advisor: Barak A. Cohen

Thesis Title: The Molecular Basis of Natural Variation in Yeast Sporulation Efficiency

Program: Computational Biology

Graduation Year: 2008

Thesis Advisor: Barak A. Cohen

Thesis Title: Decoding the Relationship Between Promoter Sequence and Gene Expression

Program affiliation
Molecular Cell Biology

Research summary
Mechanisms of chronic kidney disease progression, treatment options to halt kidney disease progression

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology
Computational and Systems Biology

Research summary
Our research focuses on unraveling the molecular mechanisms underlying substrate specificity and degradation by AAA proteolytic machines and their associated adaptor proteins, utilizing structural biology, biochemistry, and cellular assays in both bacteria and human mitochondria.

Key words
AAA proteases, cryo-EM, biochemistry, mass spectrometry, structural biology, microbiology, mitochondria

Program: Genetics

Graduation Year: 1993

Thesis Advisor: John E. Majors

Thesis Title: "Footprinting in vivo of the Rous Sarcoma Virus Transcription Control Region." Short: Footprinting in vivo of RSV u3

Program: Molecular Cell Biology

Graduation Year: 2012

Thesis Advisor: Tom Ellenberger

Thesis Title: Activation of SIRT1 by an N-terminal Regulatory Domain

Program: Genetics

Graduation Year: 1998

Thesis Advisor: Michael G. Caparon

Thesis Title: Oxidative Defense in Streptococcus pyogenes and its Role in Streptococcal Pathogenesis

Program: Computational and Systems Biology

Graduation Year: 2015

Thesis Advisor: Gautam Dantas

Thesis Title: Characterizing and Modeling Antibiotic Resistance Dynamics in Diverse Microbial Communities

Program: Neural Sciences

Graduation Year: 1990

Thesis Advisor: Jeanne M. Nerbonne

Thesis Title: Characterization and Comparison of C++ Channels in Three Identified Classes of Neurons from the Visual Cortex of Rat

Program: Evolution Ecology and Population Biology

Graduation Year: 2008

Thesis Advisor: Allan Larson

Thesis Title: Phylogeography and Diversification of Hispaniolan Ground-Dwelling Lizards, Ameiva and Leiocephalis