Paul Jones

Program: Molecular Cell Biology

Current advisor: Angela Hirbe, MD, PhD

Undergraduate university: Lake Forest College, 2015

Enrollment year: 2018

Research summary
Non-Invasive Molecular Detection and Profiling of NF1-MPNST to Guide Personalized Treatment

Graduate publications
Sundby RT, Szymanski JJ, Pan A, Jones PA, Mahmood SZ, Reid OH, Srihari D, Armstrong AE, Chamberlain S, Burgic S, Weekley K, Murray B, Patel S, Qaium F, Lucas AN, Fagan M, Dufek A, Meyer CF, Collins NB, Pratilas CA, Dombi E, Gross AM, Kim A, Chrisinger JSA, Dehner CA, Widemann BC, Hirbe AC, Chaudhuri AA, Shern JF. 2024 Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics. Clin Cancer Res, 30(19):4363-76. PMCID: PMC11443212

Szymanski JJ, Sundby RT, Jones PA, Srihari D, Earland N, Harris PK, Feng W, Qaium F, Lei H, Roberts D, Landeau M, Bell J, Huang Y, Hoffman L, Spencer M, Spraker MB, Ding L, Widemann BC, Shern JF, Hirbe AC, Chaudhuri AA. 2021 Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study. PLoS Med, 18(8):e1003734. PMCID: PMC8407545

Dehner C, Moon CI, Zhang X, Zhou Z, Miller C, Xu H, Wan X, Yang K, Mashl J, Gosline SJ, Wang Y, Zhang X, Godec A, Jones PA, Dahiya S, Bhatia H, Primeau T, Li S, Pollard K, Rodriguez FJ, Ding L, Pratilas CA, Shern JF, Hirbe AC. 2021 Chromosome 8 gain is associated with high-grade transformation in MPNST. JCI Insight, 6(6):e146351. PMCID: PMC8026192