Sadia Afrin

Program: Immunology

Current advisor: Todd A. Fehniger, MD, PhD

Undergraduate university: University of Dhaka, 2011

Enrollment year: 2022

Research summary
My research focuses on defining mechanisms of NK cell dysfunction in the multiple myeloma tumor microenvironment

Graduate publications
BACH2 regulates T cell lineage state to enhance CAR T cell function.
Chang TC, Heard A, Lattin J, Warrington JM, Barrett A, Landmann JH, Tenzin Y, Ganesh V, Thompson B, Afrin S, Gupta DK, Chang JF, Ritchey J, Selli ME, Hsu YS, Song H, Federico AJ, Horn A, Meers MP, Weber EW, Wandless TJ, Crawford JC, Thomas PG, DiPersio JF, Gottschalk S, Singh N. 2026 BACH2 regulates T cell lineage state to enhance CAR T cell function. Nat Immunol, ():Online ahead of print. PMCID:

Zhou AY, Marin ND, Afrin S, Wong P, Tran J, Jacobs MT, Becker-Hapak M, Marsala L, Foster M, Foltz JA, Neal CC, Russler-Germain DA, Morina L, Paik Y, Cubitt CC, Schappe T, Pence P, McClain E, Kelley S, Fortier J, Fiala M, Slade M, Schroeder M, Stockerl-Goldstein K, Vij R, Gao F, Berrien-Elliott MM, Fehniger TA. 2025 Memory-like NK cell differentiation, inhibitory NKG2A blockade, and improved recognition via antibody or CAR engineering combine to enhance NK cell attack against multiple myeloma. J Immunol, 214(1):1-11. PMCID: PMC11844139