Tony Yao

Program: Immunology

Current advisor: Naresha Saligrama, PhD

Undergraduate university: University of Western Ontario, 2019

Enrollment year: 2022

Research summary
Function and ontogeny of Fas-controlled T cells

Our work is focused on a CD8 T cell differentiation state that is normally eliminated by the Fas/FasL apoptotic pathway. We aim to characterize the molecular programs and cellular interactions that specify this fate.

Graduate publications
Wong P, Foltz JA, Chang L, Neal CC, Yao T, Cubitt CC, Tran J, Kersting-Schadek S, Palakurty SX, Jaeger N, Russler-Germain DA, Marin ND, Gang M, Wagner JA, Zhou AY, Jacobs MT, Foster M, Schappe T, Marsala L, McClain E, Pence P, Becker-Hapak M, Fisk B, Petti AA, Griffith OL, Griffith M, Berrien-Elliott MM, Fehniger TA. 2023 T-BET and EOMES sustain mature human NK cell identity and anti-tumor function. J Clin Invest, 133(13)::e162530. PMCID: PMC10313375