Faculty
Bahaa Elgendy, PhD
Associate Professor
- Email: belgendy@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Research summary
Medicinal chemistry with a broad goal of drug design and organic synthesis
Key words
Ali Ellebedy, PhD
Professor
- Email: ellebedy@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.
Key words
Elliot Elson, PhD
Professor Emeritus
- Email: elson@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Mechanical properties of reconstituted tissues; fluctuation spectroscopy of protein interactions
Key words
cytoskeleton, signal transduction, fluorescence correlation spectroscopy, tissue engineering, cell/tissue mechanics
Sarah England, PhD
Alan A. and Edith L. Wolff Professor
- Email: englands@wustl.edu
Program affiliation
General
Research summary
Molecular mechanisms underlying uterine function during pregnancy
Key words
women`s health, potassium channels, uterine, muscle excitability, pregnancy
Alex Evers, MD
Henry Mallinckrodt Professor and Head
- Email: eversa@wustl.edu
Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology
Research summary
Molecular mechanisms of anesthetic action - Proteomics of GABAA receptors
Key words
Anesthetics, photolabeling, mass spectrometry, proteomics
Roberta Faccio, PhD
Associate Professor
- Email: faccior@wustl.edu
Program affiliation
Molecular Cell Biology
Immunology
Cancer Biology
Research summary
interactions between bone and immune cells in inflammation and cancer
Key words
arthritis, inflammation, cancer, bone metastases, osteoclasts
Todd Fehniger, MD, PhD
Professor
- Email: tfehnige@wustl.edu
Program affiliation
Immunology
Cancer Biology
Research summary
My laboratory is focused on the molecular mechanisms regulating natural killer cell activation, novel methods to use NK cells as immunotherapy for cancer, and lymphoma genomics.
Key words
cancer, cytokine, immunology, innate immunity, NK cells, small noncoding RNAs, immunotherapy, lymphoma, genomics
Mario Feldman, PhD
Professor
- Email: mariofeldman@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Research summary
Pathogenesis of multidrug resistant bacteria and biogenesis of bacterial vesicles in the human gut
Key words
Lijuan Feng
Assistant Professor
- Email: l.feng@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Our lab studies how disease-associated histone mutations disrupt chromatin and epigenetic regulation, contributing to developmental disorders, brain inflammation, and cancer. We take a multidisciplinary approach that combines biochemical and genomic assays, molecular genetics, cell biology, and both Drosophila and mouse models to investigate how these mutations impair development and drive tumorigenesis. Current projects focus on neurodevelopmental disorders, cancer-associated histone mutations, chromatin–immune crosstalk, and the discovery of chromatin-associated factors. Through this work, we aim to uncover fundamental mechanisms of chromatin dysregulation and identify new therapeutic targets.
Key words
Chromatin, Epigenetics, Gene Regulation, Cancer, Developmental Disorders, Brain Inflammation
Thomas Ferguson, PhD
Professor
- Email: ferguson@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
Key words
angiogenesis, apoptosis, autophagy, immunology, lymphocyte, tolerance, photoreceptors, vision,