Faculty
Richard Gross, MD, PhD
Professor
- Email: rgross@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
The molecular mechanisms through which biologic membranes participate in cellular activation processes
Key words
phospholipase A2, diabetes, obesity, receptor, myocardial ischemia, lipid metabolism
C. Charles Gu, PhD
Associate Professor
- Email: gc@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Human and Statistical Genetics
Computational and Systems Biology
Research summary
Statistical genetics and bioinformatics, high-dimensional data analysis and complex systems modeling, developing novel methodologies for detecting complex disease genes and characterizing their function
Key words
genetic epidemiology, statistical genetics
Caroline Guglielmetti, PhD
Assistant Professor
Program affiliation
Neurosciences
Molecular Cell Biology
Immunology
Research summary
We develop innovative magnetic resonance (MR) and position emission tomography (PET) imaging approaches to monitor neuroinflammation, neurodegeneration and repair mechanisms in neurological disorders
Key words
Metabolic imaging, hyperpolarized 13C MRI, positron tomography emission (PET) imaging, neurological disorders, cell tracking, multiple sclerosis, microglia, myelin, immune cells
Farshid Guilak, PhD
Mildred B. Simon Research Professor
- Email: guilak@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Immunology
Research summary
Application of stem cells and mechanobiology in the onset, progression, and treatment of osteoarthritis and other joint diseases.
Key words
cartilage, obesity, osteoarthritis, mechanobiology, bioengineering, stem cells, iPSCs
Christina Gurnett, MD, PhD
Professor
- Email: gurnettc@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Research summary
Gene discovery, variant interpretation using high-throughput functional assays
Key words
genetics, genomics, sequencing, exome, development, muscle, arthrogryposis, limb, scoliosis, clubfoot
David Gutmann, MD, PhD
Donald O. Schnuck Family Professor
- Email: gutmannd@wustl.edu
Program affiliation
Neurosciences
Cancer Biology
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Research summary
Leveraging neurogenetic disorders to study normal brain development, cancer, and autism
Key words
pediatric brain cancer, brain development, neuroimmunology, cancer neuroscience, autism, hiPSC engineering, genetically engineered mice
Carmen Halabi, MD, PhD
Associate Professor
- Email: chalabi@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding how the extracellular matrix (ECM) contributes to normal arterial development and how its disruptionleads to abnormal vascular development and disease
Key words
Vascular biology, extracellular matrix, elastin, aneurysms, hypertension
Kathleen Hall, PhD
Professor
- Email: hallkathleen@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
We study RNA folding and RNA binding to proteins
Key words
RNA, NMR, RNA:protein interactions, fluorescence, thermodynamics
Dennis Hallahan, MD
Professor and Head of the Department of Radiation Oncology
- Email: dhallahan@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Research summary
The mechanisms of cell death in normal tissues during cancer therapy
Key words
cancer, cell death, drug delivery, radiation, signal transduction
Gabriel Haller, PhD
Assistant Professor
- Email: ghaller@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Research summary
Genetic underpinnings of neurological/neurosurgical disorders
Key words
rare variants, Chiari I malformation, human genetics, neurosurgery, Deep Mutation Scanning, Mutagenesis, Limb-girdle muscular dystrophy