Faculty

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology

Research summary
Relationship of structure to function in allosteric control mechanisms

Key words
protein structure, protein function, allosteric regulation, enzymology, biochemistry

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
The etiology of mutagenesis and genome instability in pediatric cancers

Key words
leukemia, pediatric cancer, DNA damage, DNA replication, hematopoiesis

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
The Greenberg lab seeks to understand the molecular and cellular biophysics of heart disease, with the goal of engineering disease models and precision therapeutics

Key words
heart disease, single molecule, optical trapping, cardiac muscle, stem cells, tissue engineering, cytoskeletal molecular motors, mechanobiology, computational modeling, precision medicine

Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
Deciphering the molecular mechanisms of epigenetics and how when this goes awry diseases arise

Key words
Epigenetics, Transgenerational, Imprinting, Evolution, Multicellularity, Cancer, Tumorigenesis, Epitranscriptomics

Program affiliation
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Cancer Biology
Computational and Systems Biology

Research summary
Improving our understanding of human disease biology and the development of personalized medicine strategies using genomics and informatics technologies

Key words
genomics, bioinformatics, data mining, immunogenomics, precision medicine, personalized medicine, cancer vaccines, and cancer research

Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Molecular Cell Biology
Immunology

Research summary
Development of personalized medicine strategies for cancer using genomic technologies

Key words
bioinformatics, machine learning, cancer, genomics, immunogenomics, precision oncology

Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology

Research summary

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
Development and application of mass spectrometry in biophysics, biochemistry, and medicine

Key words
amyloid beta biophysics, biochemistry, biophysics, mass spectrometry, protein-protein interaction, protein structure,

Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
The molecular mechanisms through which biologic membranes participate in cellular activation processes

Key words
phospholipase A2, diabetes, obesity, receptor, myocardial ischemia, lipid metabolism

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Neurosciences
Computational and Systems Biology
Molecular Cell Biology

Research summary
We work on what induces the inner ear in the first place, how the sensory organs of the ear acquire their exquisite pattern, and whether it will ever be possible to regenerate the sensory hair cells of the inner ear in the deaf and hard-of-hearing.

Key words
inner ear, development, regeneration, sensory neuroscience, balance, deafness, embryo, transcription factors, epigenetics, tunicates, squid