Faculty

Angela Hirbe, MD, PhD
Associate Professor
- Email: hirbea@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.
Key words
sarcoma, metastasis, genomics, cell signalling, NF1, MPNST

Keiko Hirose, MD
Associate Professor
- Email: hirosek@wustl.edu
Program affiliation
Neurosciences
Research summary
Innate immunity in the inner ear
Key words
inflammation, inner ear, cochlear injury, monocytes, macrophages, blood labyrinth barrier

Alex Holehouse, PhD
Assistant Professor
- Email: alex.holehouse@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Cell Biology
Plant and Microbial Biosciences
Research summary
Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
Key words

David Holtzman, MD
Andrew B. and Gretchen P. Jones Professor
- Email: holtzman@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Research summary
Cellular and Molecular studies of Alzheimer’s disease
Key words
amyloid, tau, antibodies, apolipoprotein E, Alzheimer’s disease, neurodegeneration, neurobiology

Michael Holtzman, MD
Selma and Herman Seldin Professor
- Email: mjholtzman@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Research summary
New drugs for post-viral and related types of disease
Key words
drug discovery, innate immunity, epithelial stem cells, viruses, respiratory airway disease

Timothy Holy, PhD
Alan A. and Edith L. Wolff Professor
- Email: holy@wustl.edu
Program affiliation
Neurosciences
Computational and Systems Biology
Research summary
Sensory processing and plasticity (olfaction), large-population calcium imaging, computation, social communication
Key words
calcium imaging, physiology, mathematical modeling, behavior, neurobiology, smell, olfaction, pheromones, neuroendocrine, circuits

Amjad Horani, MD
Associate Professor
- Email: horani_a@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Our lab studies airway and motile cilia biology and investigates the effects of mutations on cilia function
Key words
cilia, PCD, airway, lung


Paul Hruz, PhD, MD
Associate Professor
- Email: hruz_p@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance
Key words
protein structure, glucose transport, diabetes, AIDS, HIV therapy, membrane protein, structural biology, heart, affinity labeling, drug design

Chyi-Song Hsieh, MD, PhD
Professor
- Email: chsieh@wustl.edu
Program affiliation
Cancer Biology
Immunology
Research summary
Understanding T cell tolerance to self and non-self
Key words
autoimmunity, immunology, lymphocyte, regulatory T cell, tolerance, mucosal immunology