Faculty

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Neurosciences

Research summary
Protein folding and misfolding, and the engineering and application of protein disaggregases to reverse misfolding

Key words
protein folding and misfolding; intrinsically disordered proteins, phase separation, and neurodegenerative disease; protein chaperones; protein engineering; amyloid; yeast models of protein misfolding

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
Interactions between the nervous and genitourinary systems during development, molecular basis for heterogeneity in progenitors and their lineage commitments in the GU tract, injury and regeneration using animal models, mechanisms of malformations using organoids from iPSCs

Key words
cell fate, gene expression, genomics, disease models, growth factor signaling, kidney, bladder, innervation, stem cells, organogenesis, nervous system development, birth defects

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics

Research summary
Cancer prevention and control, health disparities and community-based research

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology
Cancer Biology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
The rational structure-based drug design and synthesis for cancer and infectious disease

Key words
protease, kinase, cancer, infection, lectin, chemistry, synthesis, drug discovery, peptidomimetic, inhibitor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis

Research summary
Characterization of human diseases associated with novel viral infections

Key words
Virology, microbiology, pathogen discovery, host-virus interactions, viral immunity, astroviruses, encephalitis, myocarditis, viral RNA structures

Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
we study the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions including cell migration, intracellular trafficking and cytokinesis.

Key words
actin cytoskeleton, microtubule, single molecule, live cell imaging, protein transport, Golgi, confocal microscopy

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary

Key words

Program affiliation
General

Research summary

Key words

Program affiliation
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology

Research summary
Exploring regulatory networks in metabolism - structural biology and biochemistry of plants and microbes

Key words
biochemistry, enzymology, plant biology, protein engineering, protein structure, structural biology

Program affiliation
Biomedical Informatics and Data Science
Cancer Biology

Research summary
Development of novel statistical methods for precision medicine

Key words
Biostatistics; Image analysis; Dynamic risk prediction; Multistate models