Faculty

Program affiliation
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Control and optimization of large-scale complex systems with applications ranging from quantum mechanics and neuroscience to bioinformatics

Key words
computational mathematics, control theory, optimization, dynamical systems, MRI, NMR, neuroscience

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary
Microglial biology and neuro-immune interactions in development, aging and disease

Key words
microglia, neuroimmunology, development, aging, neurodegeneration, single cell

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
Membrane protein structure and function

Key words
structure biology, enzymology, membrane proteins, molecular medicine, mass spectrometry, cardiovascular biology, immunology, hematology

Program affiliation
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Neurosciences

Research summary
The Li laboratory is dedicated to developing biomaterial platforms for regenerative medicine, specifically focusing on applications in angiogenesis, vascularization, stem cell engineering, and tissue regeneration.

Key words
Biomaterials, Tissue Engineering, Regenerative Medicine

Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Cancer Biology
Neurosciences

Research summary
Our research interests include developing innovative computational tools/methods and utilizing single-cell (epi)genomic techniques to gain a comprehensive understanding of gene regulation in mammalian models and human diseases, particularly in brain tumors and neuropsychiatric disorders.

Key words
Bioinformatics, Gene Regulation, Single-cell Epigenetics, Brain Tumors, Neurological Disorders

Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology

Research summary
Understanding the role of inflammation in gastrointestinal cancers

Key words
NF-kB, Toll-like receptors, IRAK4, TAK1, KRAS, ERK, MK2

Program affiliation
Neurosciences

Research summary
We study disorders of cerebrospinal fluid (CSF) physiology such as hydrocephalus and Chiari-associated syringomyelia

Key words
Pediatric neurosurgery, epilepsy surgery, neuro-endoscopy, hydrocephalus, pediatric brain tumors, deep brain stimulation, radiosurgery, pediatric spine

Program affiliation
General

Research summary
Complex systems and organizational study approaches to the study of health information exchange, health information technology use in health services, and healthcare equity

Key words

Program affiliation
Computational and Systems Biology
Ecology and Evolutionary Biology
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences

Research summary
A computational and experimental lab studying bacterial colonization and transmission at the boundary of built and natural environments and exploring microbiomes as environmental sensors and public health sentinels

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences

Research summary
Structure-function studies of Slo family K+ channels

Key words
ion channel, protein structure, neurobiology, physiology, cell signaling