Faculty

Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology

Research summary
Studying how perturbation of specific signal transduction pathways contributes to the initiation, progression and dissemination of cancer

Key words
proteomics, functional genomics, lung cancer, signal transduction, WNT, oxidative stress

Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology

Research summary
Research in the laboratory is aimed at attaining functional selectivity of opioid agonist action from its own target adverse effects while integrating chemical synthesis with biochemical, genetic and pharmacological approaches.

Key words
opioids, GPCRs, biased signaling, pain, chemical biology

Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis

Research summary
How the environment shapes host-associated microbial communities both within and across species

Key words
Gut microbiome, nonhuman primates, environmental health

Program affiliation
Plant and Microbial Biosciences
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
The Mansfeld Lab uses various non‑model species and a hypothesis driven, systems approach to examine how circadian rhythm, development, and tissue type impact plant defense.

Key words
Plant Pathology, Genomics, Bioinformatics, Disease Resistance

Program affiliation
Biomedical Informatics and Data Science
Neurosciences
Cancer Biology

Research summary
Artificial intelligence and informatics to support open science and translational research

Key words
informatics imaging AI open science

Program affiliation
Molecular Microbiology and Microbial Pathogenesis

Research summary
The cellular and molecular mechanisms that regulate the establishment and maintenance of latent neuronal infection with herpes simplex virus (HSV).

Key words

Program affiliation
Cancer Biology
Molecular Cell Biology

Research summary
Studies novel metrics to serve dual purpose as biomarkers for prognosis and response to radiation therapy, as well as therapeutic targets for human solid tumors such as cervical and anal cancers.

Key words

Program affiliation
General

Research summary
Molecular recognition is the key to drug design and the bioactive conformation.

Key words
computational biology, molecular modeling, protein structure, ErbB receptors in oncology, GPCR/G-protein, signal transduction

Program affiliation
General

Research summary

Key words

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
Development of liquid biopsy approaches for brain tumors

Key words
liquid biopsy, cfDNA, genetics, epigenetics