Faculty
Dave Pagliarini, PhD
Hugo F. and Ina C. Urbauer Professor
- Email: pagliarini@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
We seek to understand the cellular and biochemical underpinnings of mitochondrial dysfunction in human diseases. Our work integrates large-scale methodologies with traditional biochemistry and cell biology to investigate the modulation, adaptation, and basic metabolic function of mitochondria.
Key words
Mitochondria, Protein biochemistry, Genetic screening, Metabolism, Biosynthesis, Orphan protein function, Proteomics, Metabolomics, Kinases and phosphates, Metabolic disease, Systems biochemistry
Stephen Pak, PhD
Associate Professor
- Email: stephen.pak@wustl.edu
Program affiliation
General
Research summary
High-throughput drug discovery using C. elegans models of protein aggregation disorders
Key words
Himadri Pakrasi, PhD
George William and Irene Koechig Freiberg Professor
- Email: pakrasi@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
Systems and Synthetic Biology of photosynthetic organisms
Key words
Bioenergy, membrane proteins, photosynthesis, redox processes, systems biology, synthetic biology
Ben Palanca, MD, PhD, MSc
Associate Professor
- Email: palancab@wustl.edu
Program affiliation
Neurosciences
Research summary
Dr. Palanca has NIH-funded investigations on acute confusion after cardiac surgery and leveraging the anesthetic propofol to modulate sleep to treat depression and cognitive impairment.
Key words
Anesthesia, delirium, sleep, surgery, electroencephalography, imaging, fMRI, consciousness, cognition, encephalopathy, depression, antidepressant
Michael Paley, MD, PhD
Assistant Professor
- Email: paleym@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Neurosciences
Research summary
Mechanisms of inflammation in immune-privileged organs
Key words
Hua Pan, PhD
Associate Professor
- Email: hpan@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
https://sites.wustl.edu/panlab/
Key words
Onco-Nephrology, Cardio-Oncology, Cancer, MRI, Gene/drug delivery, Machine Learning
Sona Pandey, PhD
Assistant Member
- Email: sonapandey@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Research summary
To understand how plants perceive and respond to abiotic stress
Key words
heterotrimeric G-proteins, abscisic acid, G-proteins, molecular genetics, biochemistry, genomics, proteomics, protein-protein interactions
Thomas Papouin, PhD
Assistant Professor
- Email: thomas.papouin@wustl.edu
Program affiliation
Neurosciences
Research summary
Mechanisms or neuron-glia interactions in health and disease
Key words
Astrocytes, Synapses, Neuromodulation, Behavior, Electrophysiology,
Rohit Pappu, PhD
Gene K Beare Distinguished Professor
- Email: pappu@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Plant and Microbial Biosciences
Research summary
Biophysics of intrinsically disordered proteins
Key words
Huntington`s disease; Polyglutamine Aggregation; Intrinsically Disordered Proteins; Phase transitions in cell biology; Self-assembly; Transcriptional regulation; Small-scale Systems Biology & Interaction Networks;
Yikyung Park, MS/ScD
Associate Professor
- Email: yikyungpark@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Research summary
Key words
Nutrition, Cancer, Epidemiology, Risk prediction, Population health