Faculty
Philip Payne, PhD, FACMI
Janet and Bernard Becker Professor
- Email: prpayne@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Translational Bioinformatics, Clinical Research Informatics
Key words
Biomedical Informatics, Data Science, Data Analytics, Clinical Research, Translational Research
Jacqueline Payton, MD, PhD
Associate Professor
- Email: jpayton@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Biomedical Informatics and Data Science
Molecular Microbiology and Microbial Pathogenesis
Research summary
Epigenomic aberrations in B cell lymphomas and their impact on gene regulation
Key words
epigenomics, cancer, lymphoma, histone, informatics, genomics, gene regulation
Rachel Penczykowski, PhD
Associate Professor
- Email: rpenczykowski@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences
Research summary
The ecology and evolution of infectious diseases, with a focus on wild populations of herbaceous plant hosts and their powdery mildew pathogens.
Key words
host-parasite interactions, disease ecology, plant pathogens, urban ecology, climate change
Guangyong Peng, MD, PhD
Professor
- Email: pengg@wustl.edu
Program affiliation
Immunology
Cancer Biology
Neurosciences
Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.
Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy
Toby Pennington, DPhil
David and Dorothy Kemper Professor
- Email: ptoby@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Molecular Genetics and Genomics
Plant and Microbial Biosciences
Research summary
Key words
Toby Pennington, D.Phil
David and Dorothy Kemper Professor
- Email: ptoby@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Molecular Genetics and Genomics
Plant and Microbial Biosciences
Research summary
Key words
Susan Perlman, PhD
Associate Professor
- Email: perlmansusan@wustl.edu
Program affiliation
Neurosciences
Research summary
Key words
David Perlmutter, MD
Spencer T. and Ann W. Olin Distinguished Professor
- Email: perlmutterd@wustl.edu
Program affiliation
Molecular Cell Biology
Immunology
Molecular Genetics and Genomics
Research summary
Pathobiology of liver disease from accumulation and proteotoxicity of misfolded proteins in α1-antitrypsin deficiency; role of autophagy in biology and treatment of disorders caused by misfolded proteins
Key words
α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs
Joel Perlmutter, MD
Professor
- Email: perlmutterjoel@wustl.edu
Program affiliation
Neurosciences
Research summary
Pharmacology, physiology and pathophysiology of basal ganglia and movement disorders
Key words
pathogenesis, neuroimaging, physiology, neurobiology, movement disorders, Parkinson disease, dystonia
Stephen Persaud, MD,PhD
Assistant Professor
- Email: persaud@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Research summary
Optimizing hematopoietic stem cell transplantation as definitive therapy for non-malignant blood diseases
Key words
sickle cell disease, hematopoietic stem cell transplantation, antibody-based immunotherapy, conditioning, JAK inhibitors, gene editing
