Faculty

Program affiliation
Developmental Regenerative and Stem Cell Biology

Research summary
Direct reprogramming of cells into specialized cardiac conduction tissues

Key words
conduction system, reprogramming, heart development, Notch, arrhythmia, regenerative medicine, mouse models

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Neurosciences

Research summary
Understanding the neuroimmune basis of infectious and non-infectious diseases

Key words
Pain and sensory disorders; Infectious diseases; Neuroimmunology; Host-microbe interactions

Program affiliation
Cancer Biology

Research summary
Molecular imaging tools to understand tumor biology and response to therapies

Key words
cancer, imaging, therapy, antibody, membrane receptors, radiochemistry

Program affiliation
General

Research summary
Statistical genetics; complex disease genetics; methods in statistical genetics

Key words
mathematical modeling, epidemiology, genetics

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Cancer Biology
Molecular Cell Biology

Research summary
The Brain Development and Disorders Laboratory investigates how long-range neural circuits are established in the brain, and how neural circuit plasticity affects the function of the cerebral cortex.

Key words
cognitive and behavioral neuroscience, developmental neurobiology, molecular and cellular neuroscience, neurogenetics, cerebral cortex, corpus callosum, glial development, neuronal development, brain wiring, agenesis

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
Using bench molecular biology, high-throughput sequencing, and bioinformatics to understand human inflammatory / autoimmune disease.

Key words
human genetics; autoimmune; inflammatory disease; biomarkers; high-throughput sequencing; precision medicine

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Neurosciences

Research summary
To understand how and why membrane proteins fold, form stable complexes, and achieve conformational stability inside of the oil-filled cell membrane.

Key words
membrane protein; single-molecule; TIRF microscopy; protein folding; thermodynamics; lipids; oligomerization

Program affiliation
General

Research summary

Key words

Program affiliation
Neurosciences

Research summary
Investigating the relationship between neonatal brain development, early life adversity and childhood psychiatric disorders in high risk infant populations

Key words

Program affiliation
Neurosciences

Research summary
My research aims to understand of how brain networks develop and adapt to changes caused by epilepsy, tumors, stroke, and or other neurological injuries. In particular I am interested in how children's brains reorganize after neurosurgical treatment of these conditions.

Key words
intracranial electroencephalography, ieeg, resting state functional MRI, rs-fMRI, brain networks, development, epilepsy, neurosurgery