Faculty

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
We use zebrafish as a model for human hearing and balance with the goal of protecting and repairing inner ears from damage.

Key words
zebrafish, sensory neuroscience, hearing, balance, synaptic physiology, regeneration

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Understand the structural mechanisms of host-pathogen interactions and the inflammasome signaling

Key words
structural biology, innate immunity, pattern recognition receptors, immune recognition, inflammasomes

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Focused on injury, repair, and regeneration of musculoskeletal tissues with the goal to understand the progenitor cell population, signals, and role of inflammation on tissue injury and regeneration at the cellular and molecular level

Key words

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Immunology
Neurosciences

Research summary
My research program integrates cardiovascular physiology, stem cell biology, developmental biology, functional genomics, and cardio-oncology to investigate molecular mechanisms of congenital and acquired cardiovascular diseases. My laboratory specializes in developing innovative protocols for generating authentic cardiovascular cell types from human induced pluripotent stem cells (iPSCs), advancing cardiovascular precision medicine. We aim to bridge basic science and clinical translation through disease modeling, therapeutic target identification, and adverse outcome prevention.

Key words
iPSC, CRISPR, organoid, cardiovascular, precision medicine, cardio-oncology

Program affiliation
Neurosciences

Research summary
Translational Brain MRI Clinical Applications; Neurophysiology Modeling Using MRI Methods

Key words
brain, imaging, magnetic resonance imaging, fMRI, DTI, perfusion, mathematical modeling

Program affiliation
General

Research summary
Clinical genomics and the application of exome and genome sequencing as well as microarray analysis for disease gene discovery

Key words
genomic medicine, disease gene discovery, metabolic disorders, and skeletal dysplasias

Program affiliation
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Develop optical imaging technologies that address clinical problems with a focus on dermatology

Key words
dermatology imaging engineering pigmentation global heath

Program affiliation
Computational and Systems Biology
Cancer Biology
Biomedical Informatics and Data Science
Neurosciences

Research summary
I have multidisciplinary research interests spanning disease biology, engineering, imaging sciences, and informatics. Our work integrates computational imaging, artificial intelligence, and clinical/translational medicine to discover and validate quantitative imaging biomarkers and to define therapeutic endpoints in cancer and other diseases.

Key words
Computational medicine, cancer, systems biology and quantitative imaging

Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Immunology

Research summary
Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases

Key words

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology

Research summary
Cellular and molecular basis of intracellular parasitism by protozoan parasites

Key words
cell-signaling, kinases, transcription, chromatin, pathogenesis, genetics, genomics, chemical biology, innate immunity