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Leonid Shmuylovich, MD,PhD

Assistant Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Develop optical imaging technologies that address clinical problems with a focus on dermatology

Key words
dermatology imaging engineering pigmentation global heath

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Kooresh Shoghi, PhD

Professor

Program affiliation
Computational and Systems Biology
Cancer Biology
Biomedical Informatics and Data Science
Neurosciences

Research summary
I have multidisciplinary research interests spanning disease biology, engineering, imaging sciences, and informatics. Our work integrates computational imaging, artificial intelligence, and clinical/translational medicine to discover and validate quantitative imaging biomarkers and to define therapeutic endpoints in cancer and other diseases.

Key words
Computational medicine, cancer, systems biology and quantitative imaging

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Monica Shokeen, PhD

Associate Professor

Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Immunology

Research summary
Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases

Key words

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L. David Sibley, PhD

Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology

Research summary
Cellular and molecular basis of intracellular parasitism by protozoan parasites

Key words
cell-signaling, kinases, transcription, chromatin, pathogenesis, genetics, genomics, chemical biology, innate immunity

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Jonathan Silva, PhD

Associate Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
Engineering to help cardiac arrhythmia patients feel better and live longer.

Key words
Bioelectricity, Arrhythmias, Modeling, Molecular Imaging, Electrophysiology, Induced Pluripotent Stem Cells

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Matthew Silva, PhD

Professor

Program affiliation
Molecular Cell Biology
Human and Statistical Genetics

Research summary
Skeletal mechanobiology; bone strength; osteoporosis; bone fracture, repair & regeneration

Key words
bone mechanics, bone biology, injury, mechanotransduction, mouse models, osteoporosis

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Jessica Silva-Fisher, PhD

Assistant Professor

Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology

Research summary
Long non-coding RNAs and RNA modifications in cancer metastasis and aggressive disease

Key words
Cancer metastasis, multiple myeloma, breast cancer, long non-coding RNAs, RNA modifications, genomics, advanced sequencing, epitranscriptomics

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Srikanth Singamaneni, PhD

Associate Professor

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
Plasmonic biosensors and biomimetic sensors

Key words
biomimetic sensors, plasmonic biosensors, nanostructures, transduction platforms

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Nathan Singh, MD, MS

Associate Professor

Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding how synthetic antigen receptors direct T cell function and dysfunction in the treatment of blood cancers

Key words
CAR T cell therapy, immunotherapy for cancer, T cell signaling, T cell dysfunction, lineage decisions

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James Skeath, PhD

Professor

Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences

Research summary
Genetic analysis of neural and muscular development in the Drosophila embryo

Key words
development, neurobiology, cell signaling