Faculty

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Biomedical Informatics and Data Science
Molecular Genetics and Genomics

Research summary

Key words
protein design, protein engineering, influenza, RSV, machine learning , vaccines, antivirals

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biomedical Informatics and Data Science

Research summary
Infectious causes of cancer and chronic diseases

Key words

Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
We computationally model drug metabolism to predict drug toxicity and to assist pathologists in assessing histology images.

Key words
deep learning, metabolism, pathology, image analysis, machine learning, bioinformatics, biostatistics, chemical informatics, drug and target discovery, drug design

Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Identify and define those molecular features that drive leukemogenesis and then use that information to develop rational therapeutic strategies for improving outcomes in acute leukemia

Key words
leukemia, metabolism, therapy resistance, stem cells

Program affiliation
Neurosciences

Research summary
Characterizing functional brain network development in children with and without anxiety disorders, with the long-term goal of using this information to devise novel, mechanism-based treatments for pediatric anxiety disorders.

Key words

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Circadian physiology and behavior

Key words
circadian rhythm, neuropeptide, GPCR, 2nd messengers, Drosophila

Program affiliation
Immunology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
Our research focuses on employing multi-omics strategies to elucidate mechanisms of immune tolerance, identify novel targets for immunosuppression and develop precision approaches to immunosuppression management in advanced lung disease and lung transplantation.

Key words
immunology, genetics, T cell, neutrophil, transplant, pharmacogenetics, pharmacogenomics, immunogenetics, immunogenomics, clonal hematopoiesis, senescence, immune aging

Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Immunology
Molecular Cell Biology
Neurosciences

Research summary
Cancer-Stroma interactions in metastasis

Key words
cancer metastasis; tumor microenvironment, cancer immunology, CRISPR screen, quantitative biology

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
The biological regulation of skeletal matrix quality

Key words

Program affiliation
Computational and Systems Biology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Metabolism analysis and metabolic engineering of environmental microorganisms for biofuel/chemical production

Key words
Metabolic flux analysis, bioenergy, metabolic engineering, algal bioprocess, bioremediation, kinetic modeling