Faculty

Program affiliation
Immunology
Cancer Biology
Neurosciences

Research summary
We study the antigen specificity and function of CD8 T cells in the context of neurodegeneration and cancer

Key words
T cells, Amyotrophic Lateral Sclerosis, antigen specificity, cancer

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
We study disease-relevant cell and organ signaling pathways in inflammatory bowel disease using molecular and cell biology, multi-omics technologies, genetic murine models, and patient samples.

Key words
inflammatory bowel disease, mucosal immunity, innate lymphoid cells, human intestinal organoids, regenerative medicine, biomarker discovery, cellular stress response, perianal fistulizing Crohn's disease, eosinophilic esophagitis, colon cancer

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology

Research summary
Novel genetic, microbial, and lifestyle risk factors for lung and gastrointestinal cancers leveraging large-scale clinical and population-based cohorts with deep genomic and phenotypic data

Key words
Systems and translational cancer epidemiology, microbiome, inflammation and immune-metabolic networks

Program affiliation
Neurosciences

Research summary
mechanisms and treatments of chronic migraine and post-traumatic headache

Key words
ion channel, neuroimmune interaction, chronic migraine, post-traumatic headache, chronic pain and comorbidity, synaptic transmission, neuronal excitability

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics

Research summary
Genetics and virulence of the pathogenetic streptococci

Key words
bacteriology, gene expression, inflammation, microbial pathogenesis, toxin

Program affiliation
Neurosciences
Ecology and Evolutionary Biology
Computational and Systems Biology

Research summary
Sensory and Evolutionary Neuroscience

Key words
neural circuits, neurophysiology, sensory systems, behavior, evolution, mathematical modeling

Program affiliation
Plant and Microbial Biosciences

Research summary
Focus on the biogenesis, functions, and evolutionof small RNA-directed silencing pathways in multicellular eukaryotes

Key words
genomics, functional genomics, biogenesis, systems biology, silencing pathways, plant biology, molecular biology, bioinformatics, RNA pathways

Program affiliation
Neurosciences

Research summary
Network plasticity as it pertains to neurorehabilitation, particularly in recovery from stroke

Key words
stroke, resting state connectivity, brain

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Understanding the role of endogenous opioids in affective neuroscience and metabolic homeostasis

Key words
reward, valence, opioid, motivation, metabolism, diabetes

Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Cellular, Molecular and Epigenetic control of axon regeneration

Key words
axon regeneration, nerve injury, epigenetic, transcription, glia biology, neuroimmune mechanisms, spinal cord injury, optic nerve injury