Mentorship Certified
Grant Challen, PhD
Assistant Professor
- Email: grantchallen@wustl.edu
Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
Key words
Hematopoietic stem cells, Leukemia stem cells, Epigenetic modifications
Shiming Chen, PhD
Dr. Bernard and Janet R. Becker Distinguished Professor
- Email: chenshiming@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences
Research summary
Molecular mechanisms regulating photoreceptor gene expression in healthy and diseased retinas
Key words
Gene expression regulation, transcription factors, epigenetic regulators, photoreceptor development and degeneration, mouse models, gene therapy
Jonathan Cooper, PhD
Professor
- Email: cooperjd@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology
Research summary
Disease mechanisms and treatments for inherited childhood neurodegeneration
Key words
Batten Disease, Neuronal Ceroid Lipofuscinosis, NCL, Lysosomal Storage Disease, pathogenesis, pre-clinical therapies, enzyme replacement, gene therapy