Mentorship Certified

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Human and Statistical Genetics

Research summary
We use human genetic, functional genomic, and bioinformatic approaches to understand the consequence of genetic variants underlying diseases

Key words
Functional genomics, bioinformatics, human genetics, data science, rare diseases, pain

Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology

Research summary
Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose

Key words
Hematopoietic stem cells, Multipotent progenitors, Cell fate decision, Lineage specification, Stem cell biology, Cancer (myeloid leukemia), Aging

Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology

Research summary
A major component of my research program is to (1) develop strategies for improving the therapeutic ratio of radiation therapy by increasing tumor sensitivity to radiation and limiting normal tissue toxicity and (2) understand the biological mechanisms of treatment resistance.

Key words
Cancer targeting, antibodies, Translational research, Radiation, Lung Cancer, Glioblastoma, Signaling mechanisms

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology

Research summary
My goal is to understand how CAR T cells interact with their immune environment, and to manipulate these interactions to improve outcomes of treatment.

Key words
CAR T cells, HSCs, cell therapy, gene therapy, cancer

Program affiliation
Neurosciences

Research summary
circadian system influence on the limbic system during Alzheimer's disease pathogenesis and aging

Key words
Alzheimer's Disease, Circadian System, Hippocampal Physiology, Neurodegeneration

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Cell Biology
Biomedical Informatics and Data Science

Research summary
Modulating the complement system to mitigate pneumonia and acute lung injury

Key words
complement, pneumonia, lung injury, transplant, ICU, translational

Program affiliation
Immunology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Investigating the development of immunological memory in disease states

Key words
B cells, immunological memory, germinal center, virus, allergy

Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology

Research summary
Bacterial growth and antibiotic susceptibility

Key words
Bacterial, growth size, antibiotics, tolerance, antibiotic resistance, systems biology, cytoskeleton, biochemistry, microbiology, microscopy

Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Cancer Biology
Neurosciences

Research summary
Our research interests include developing innovative computational tools/methods and utilizing single-cell (epi)genomic techniques to gain a comprehensive understanding of gene regulation in mammalian models and human diseases, particularly in brain tumors and neuropsychiatric disorders.

Key words
Bioinformatics, Gene Regulation, Single-cell Epigenetics, Brain Tumors, Neurological Disorders

Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis

Research summary
How the environment shapes host-associated microbial communities both within and across species

Key words
Gut microbiome, nonhuman primates, environmental health