Mentorship Certified

Program affiliation
General

Research summary
circadian system influence on the limbic system during Alzheimer's disease pathogenesis and aging

Key words
Alzheimer's Disease, Circadian System, Hippocampal Physiology, Neurodegeneration

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology

Research summary
Human immunodeficiency virus-host interactions

Key words

Program affiliation
Immunology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Investigating the development of immunological memory in disease states

Key words
B cells, immunological memory, germinal center, virus, allergy

Program affiliation
Neurosciences
Computational and Systems Biology

Research summary

Key words

Program affiliation
Biomedical Informatics and Data Science
Neurosciences

Research summary
The Lee Laboratory develops computational approaches to advance precision medicine through retinal imaging, artificial intelligence, and multimodal biomedical data. Our research integrates ophthalmic imaging, clinical phenotypes, wearable sensors, electronic health records, and multi-omics to discover noninvasive biomarkers of systemic diseases, including diabetes, Alzheimer's disease, and cardiovascular disease. Through large-scale collaborative studies such as Eye ACT, AI-READI, and the Framingham Heart Study Eye Project, we build open, AI-ready resources that accelerate scientific discovery and improve patient care.

Key words
Big Data, AI, Ophthalmology, Clinical Epidemiology, Alzheimer's, Oculomics

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary

Key words

Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology

Research summary
Bacterial growth and antibiotic susceptibility

Key words
Bacterial, growth size, antibiotics, tolerance, antibiotic resistance, systems biology, cytoskeleton, biochemistry, microbiology, microscopy

Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Cancer Biology
Neurosciences

Research summary
Our research interests include developing innovative computational tools/methods and utilizing single-cell (epi)genomic techniques to gain a comprehensive understanding of gene regulation in mammalian models and human diseases, particularly in brain tumors and neuropsychiatric disorders.

Key words
Bioinformatics, Gene Regulation, Single-cell Epigenetics, Brain Tumors, Neurological Disorders

Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary

Key words

Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology

Research summary
Research in the laboratory is aimed at attaining functional selectivity of opioid agonist action from its own target adverse effects while integrating chemical synthesis with biochemical, genetic and pharmacological approaches.

Key words
opioids, GPCRs, biased signaling, pain, chemical biology