Biochemistry Biophysics and Structural Biology
Guy Genin, PhD
Harold & Kathleen Faught Professor
- Email: genin@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Plant and Microbial Biosciences
Research summary
Interfaces and adhesions in physiology and nature
Key words
mechanics, physics, interfaces, adhesion, mechanobiology, strain mapping, viscoelasticity
Aliereza Ghanbarpour, PhD
Assistant Professor
- Email: alirezag@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology
Computational and Systems Biology
Research summary
Our research focuses on unraveling the molecular mechanisms underlying substrate specificity and degradation by AAA proteolytic machines and their associated adaptor proteins, utilizing structural biology, biochemistry, and cellular assays in both bacteria and human mitochondria.
Key words
AAA proteases, cryo-EM, biochemistry, mass spectrometry, structural biology, microbiology, mitochondria
Daniel Goldberg, MD, PhD
Professor
- Email: dgoldberg@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Biochemistry of malaria
Key words
biochemistry, metabolism, parasitology, malaria, protease, heme, aspartic
Dennis Goldfarb, PhD
Assistant Professor
- Email: d.goldfarb@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Computational mass spectrometry and proteomics
Key words
Mass Spectrometry, Proteomics, Bioinformatics
Gary Grajales, MD,PhD
Assistant Professor
- Email: ggary@wustl.edu
Program affiliation
Immunology
Neurosciences
Biomedical Informatics and Data Science
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Key words
Gregory Grant, PhD
Professor
- Email: ggrant@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Relationship of structure to function in allosteric control mechanisms
Key words
protein structure, protein function, allosteric regulation, enzymology, biochemistry
Michael Greenberg, PhD
Associate Professor
- Email: greenberg@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
The Greenberg lab seeks to understand the molecular and cellular biophysics of heart disease, with the goal of engineering disease models and precision therapeutics
Key words
heart disease, single molecule, optical trapping, cardiac muscle, stem cells, tissue engineering, cytoskeletal molecular motors, mechanobiology, computational modeling, precision medicine
Michael Gross, PhD
Professor
- Email: mgross@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Development and application of mass spectrometry in biophysics, biochemistry, and medicine
Key words
amyloid beta biophysics, biochemistry, biophysics, mass spectrometry, protein-protein interaction, protein structure,
Richard Gross, MD, PhD
Professor
- Email: rgross@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
The molecular mechanisms through which biologic membranes participate in cellular activation processes
Key words
phospholipase A2, diabetes, obesity, receptor, myocardial ischemia, lipid metabolism
Kathleen Hall, PhD
Professor
- Email: hallkathleen@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
We study RNA folding and RNA binding to proteins
Key words
RNA, NMR, RNA:protein interactions, fluorescence, thermodynamics