Cancer Biology

Program affiliation
Biochemistry Biophysics and Structural Biology
Cancer Biology
Computational and Systems Biology
Molecular Cell Biology

Research summary

Key words

Program affiliation
Molecular Cell Biology
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary
Understanding the role of DNA damage and RNA degradation during tissue homeostasis, regeneration, aging, and cancer

Key words
DNA damage; DNA repair; Telomerase; Stem cell biology; Cancer; Aging

Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury

Key words

Program affiliation
Molecular Cell Biology
Cancer Biology
Biochemistry Biophysics and Structural Biology

Research summary
Tumor cell biology, signal transduction, and drug development

Key words
cancer, signal transduction, molecular pharmacology, autophagy, metabolism, drug development

Program affiliation
Human and Statistical Genetics
Computational and Systems Biology
Cancer Biology

Research summary
The interplay between inherited genetic variation, environmental factors, and acquired mutations in shaping the earliest stages of carcinogenesis

Key words
cancer, genetics, computational biology, genetic epidemiology

Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Genomics and Cell Signaling in Breast Cancer

Key words
cancer, genomics, organoids, 3D culture, receptor tyrosine kinase, signal transduction, next-generation sequencing, targeted therapy of cancer

Program affiliation
Cancer Biology

Research summary
We are interested in the neurodevelopmental and environmental factors that affect the risk of brain tumor development and cognitive impairment in children.

Key words
pediatric, glioma, obesity, neurofibromatosis, neurodevelopment

Program affiliation
Immunology
Cancer Biology
Neurosciences

Research summary
We study the antigen specificity and function of CD8 T cells in the context of neurodegeneration and cancer

Key words
T cells, Amyotrophic Lateral Sclerosis, antigen specificity, cancer

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology

Research summary
Novel genetic, microbial, and lifestyle risk factors for lung and gastrointestinal cancers leveraging large-scale clinical and population-based cohorts with deep genomic and phenotypic data

Key words
Systems and translational cancer epidemiology, microbiome, inflammation and immune-metabolic networks

Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells

Key words
Hematopoietic stem cells, Leukemia stem cells, Epigenetic modifications