Cancer Biology
Matthew Walter, MD
Professor
- Email: mjwalter@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Research summary
Genetics and genomics of blood cancer: mutation discovery and mouse models
Key words
cancer, functional genomics, gene expression profiling, hematopoiesis, stem cells, tumor biology
Jennifer Wang, PhD
Assistant Professor
- Email: wjennifer@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Cancer Biology
Neurosciences
Research summary
We study how subcellular compartments are organized to create functional molecular machines
Key words
Subcellular organization, centrosomes, cilia, microtubules, cytoskeleton, organelles
Jeffrey Ward, MD, PhD
Assistant Professor
- Email: jward2@wustl.edu
Program affiliation
Cancer Biology
Immunology
Research summary
Identification of tumor specific mutant antigens recognized by the immune system as foreign that serve as the target of a T-cell response against tumors
Key words
Mark Watson, MD, PhD
Professor
- Email: watsonm@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Human and Statistical Genetics
Research summary
Detection and molecular classification of rare tumor cells to predict and mitigate cancer metastases
Key words
cancer, functional genomics, gene expression, pathogenesis, breast cancer
Max Wattenberg, MD
Assistant Professor
- Email: wattenberg@wustl.edu
Program affiliation
Cancer Biology
Immunology
Research summary
We are focused on exploiting features of the tumor microenvironment for cancer therapy. Specifically, we study stromal - tumor cell interactions in pancreatic cancer with the goal of defining clinically relevant cancer biology.
Key words
pancreatic cancer, immunotherapy, myeloid cells, tumor microenvironment, CRISPR screening
Jason Weber, PhD
Professor
- Email: jweber@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Tumor suppressor and oncogene networks in cancer biology
Key words
Breast cancer, lung cancer, tumor suppressors, oncogenes, microfluidics, RNA editing, metastasis
Katherine Weilbaecher, MD
Professor
- Email: kweilbae@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Molecular mechanisms through which tumor cells metastasize to bone
Key words
cancer, bone biology, integrin biology, metastasis
Jinbin Xu, PhD
Associate Professor
- Email: jinbinxu@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology
Cancer Biology
Research summary
Alzheimer’s disease, Parkinson's disease, central nervous disorders, postmortem biomarker validation and characterization, in vivo positron emission tomography, in vitro quantitative autoradiography
Key words
Imaging, biomarkers, cancer, neuroscience, PET, quantitative autoradiography, pharmaceuticals, biological assays, human brain function and disease
Zhongsheng You, PhD
Professor
- Email: zyou@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Cancer Biology
Research summary
DNA and RNA surveillance mechanisms and their relation to cancer formation and treatment
Key words
cancer, replication stress response, DNA damage response, nonsense-mediated RNA decay, genetically-encoded reporters, cell imaging
Mohamed Zayed, MD,PhD
Associate Professor
- Email: zayedm@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
The mechanisms that influence arterial collateral formation and peripheral arterial atheroprogression in the setting of diabetes
Key words