Human and Statistical Genetics
Gerald Dorn, II, MD
Philip & Sima K Needleman Professor
- Email: gdorn@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Research summary
Cellular, Molecular, And Genetic Studies Of Cardiac Hypertrophy And Heart Failure
Key words
cell death, cell signaling, genetic epidemiology, heart failure
Joseph Dougherty, PhD
Professor
- Email: jdougherty@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Computational and Systems Biology
Human and Statistical Genetics
Research summary
Human Psychiatric Genetics, Mouse Models, Cell Type Specific Gene Expression Profiling, Translation, Astrocytes.
Key words
autism, gene expression profiling, genetics, genomics, mouse models, neurobiology, astrocytes, translation regulation
Susan Dutcher, PhD
Professor
- Email: dutcher@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Molecular Cell Biology
Human and Statistical Genetics
Plant and Microbial Biosciences
Research summary
Key words
centrioles, cilia, signal transduction, cytoskeleton,
John Edwards, PhD
Associate Professor
- Email: jredwards@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Research summary
We develop new computational and experimental approaches to understand the roles of DNA methylation and hydroxymethylation in neurodevelopment and cancer
Key words
bioinformatics, cancer, cancer genomics, epigenetics, epigenomics, neurodevelopment, transcriptional regulation
Stephanie Fritz, MD, MSCI
Associate Professor
- Email: fritz.s@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Microbiology and Microbial Pathogenesis
Research summary
Asking and answering critical questions to guide clinical practice and ameliorate childhood suffering due to staphylococcal disease
Key words
Staphylococcus aureus; antibiotic resistance; epidemiology; infection treatment and prevention; genomic determinants of disease; host immune response
C. Charles Gu, PhD
Associate Professor
- Email: gc@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Human and Statistical Genetics
Computational and Systems Biology
Research summary
Statistical genetics and bioinformatics, high-dimensional data analysis and complex systems modeling, developing novel methodologies for detecting complex disease genes and characterizing their function
Key words
genetic epidemiology, statistical genetics
Gabriel Haller, PhD
Assistant Professor
- Email: ghaller@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Research summary
Genetic underpinnings of neurological/neurosurgical disorders
Key words
rare variants, Chiari I malformation, human genetics, neurosurgery, Deep Mutation Scanning, Mutagenesis, Limb-girdle muscular dystrophy
Andrew Heath, DPhil
Spencer T. Olin Professor of Psychology
- Email: aheath@wustl.edu
Program affiliation
Human and Statistical Genetics
Ecology and Evolutionary Biology
Biomedical Informatics and Data Science
Research summary
Genetic studies of alcoholism, smoking and drug dependence, depression, suicidality and anxiety disorders, personality disorders, and methodological research in genetic epidemiology
Key words
substance abuse, development, modeling, psychiatry, quantitative genetics