Immunology
Kenneth Murphy, MD, PhD
Eugene Opie First Centennial Professor
- Email: kmurphy@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Dendritic cell development and diversification
Key words
Dendritic cell and T cell differentiation, gene expression, transcription, inflammation
Rodney Newberry, MD
Professor
- Email: rnewberry@wustl.edu
Program affiliation
Immunology
Research summary
Mucosal Immunology
Key words
Immunology, Gastrointestinal Tract, Inflammatory Bowel Disease
Stephen Oh, MD, PhD
Professor
- Email: stoh@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Immunology
Research summary
Mechanisms of dysregulated signaling in blood cancers
Key words
cancer biology, signal transduction, JAK2, leukemia, hematopoiesis, stem cells, mass cytometry, CyTOF, genomics
Miranda Orr, PhD
Associate Professor
- Email: orr.m@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Computational and Systems Biology
Immunology
Research summary
Key words
Anthony Orvedahl, MD, PhD
Assistant Professor
- Email: aorvedahl@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understanding factors that regulate host immune responses to infectious and sterile triggers of severe inflammation
Key words
Russell Pachynski, MD
Associate Professor
- Email: rkpachynski@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Research summary
Key words
Michael Paley, MD, PhD
Assistant Professor
- Email: paleym@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Neurosciences
Research summary
Mechanisms of inflammation in immune-privileged organs
Key words
Hua Pan, PhD
Associate Professor
- Email: hpan@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
https://sites.wustl.edu/panlab/
Key words
Onco-Nephrology, Cardio-Oncology, Cancer, MRI, Gene/drug delivery, Machine Learning
Guangyong Peng, MD, PhD
Professor
- Email: pengg@wustl.edu
Program affiliation
Immunology
Cancer Biology
Neurosciences
Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.
Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy
David Perlmutter, MD
Spencer T. and Ann W. Olin Distinguished Professor
- Email: perlmutterd@wustl.edu
Program affiliation
Molecular Cell Biology
Immunology
Molecular Genetics and Genomics
Research summary
Pathobiology of liver disease from accumulation and proteotoxicity of misfolded proteins in α1-antitrypsin deficiency; role of autophagy in biology and treatment of disorders caused by misfolded proteins
Key words
α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs