Immunology
Michael Paley, MD, PhD
Assistant Professor
- Email: paleym@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Neurosciences
Research summary
Mechanisms of inflammation in immune-privileged organs
Key words
Hua Pan, PhD
Associate Professor
- Email: hpan@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
https://sites.wustl.edu/panlab/
Key words
Onco-Nephrology, Cardio-Oncology, Cancer, MRI, Gene/drug delivery, Machine Learning
Guangyong Peng, MD, PhD
Professor
- Email: pengg@wustl.edu
Program affiliation
Immunology
Cancer Biology
Neurosciences
Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.
Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy
David Perlmutter, MD
Spencer T. and Ann W. Olin Distinguished Professor
- Email: perlmutterd@wustl.edu
Program affiliation
Molecular Cell Biology
Immunology
Molecular Genetics and Genomics
Research summary
Pathobiology of liver disease from accumulation and proteotoxicity of misfolded proteins in α1-antitrypsin deficiency; role of autophagy in biology and treatment of disorders caused by misfolded proteins
Key words
α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs
Christine Pham, MD
G & EM Magness Professor
- Email: cpham@wustl.edu
Program affiliation
Immunology
Molecular Genetics and Genomics
Research summary
Immunity and autoimmunity in inflammatory diseases; nanotherapy in the treatment of inflammatory diseases
Key words
autoimmunity, inflammation, innate immunity, nanotechnology, protease
Jennifer Philips, MD, PhD
Theodore and Bertha Bryan Professor
- Email: philips.j.a@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Cell Biology
Research summary
Immune Evasion by Mycobacterium tuberculosis
Key words
tuberculosis, host-pathogen interactions, innate immunity, autophagy, lipid metabolism, phagosome maturation, antigen presentation, macrophage
Sumanth Prabhu, MD
Tobias & Hortense Lewin Distinguished Professor of Cardiovascular Disease
- Email: prabhu@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Cell Biology
Research summary
Key words
Gwendalyn Randolph, PhD
Emil R. Unanue Distinguished Professor
- Email: gjrandolph@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
We focus on inter-organ communication and the transit of cells and molecules out of tissues in healthy and disease states
Key words
lymphatic vessels, lymph nodes, IBD, monocytes, macrophages, high-density lipoprotein, peritoneal tumor metastasis, peritoneal macrophages
Kodi Ravichandran, PhD
Robert L. Kroc Professor and BJC Investigator
- Email: kodi@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Research summary
Apoptotic cell clearance mechanisms in health and disease
Key words
Felipe Ribeiro, PhD
Assistant Professor
- Email: dfelipe@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Neurosciences
Research summary
Understanding the neuroimmune basis of infectious and non-infectious diseases
Key words
Pain and sensory disorders; Infectious diseases; Neuroimmunology; Host-microbe interactions