Immunology

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology

Research summary
Molecular pathogenesis of Mycobacterium tuberculosis

Key words
bacteria, gene regulation, molecular genetics, microbiology, pathogenesis, transcription, infectious disease, innate immunity

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Investigate the genetic and environmental factors that underlie the mechanistic basis for the heterogeneity in outcomes in response to infection

Key words

Program affiliation
Immunology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
Our research focuses on employing multi-omics strategies to elucidate mechanisms of immune tolerance, identify novel targets for immunosuppression and develop precision approaches to immunosuppression management in advanced lung disease and lung transplantation.

Key words
immunology, genetics, T cell, neutrophil, transplant, pharmacogenetics, pharmacogenomics, immunogenetics, immunogenomics, clonal hematopoiesis, senescence, immune aging

Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Immunology
Molecular Cell Biology
Neurosciences

Research summary
Cancer-Stroma interactions in metastasis

Key words
cancer metastasis; tumor microenvironment, cancer immunology, CRISPR screen, quantitative biology

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Immunology

Research summary
Naive pluripotency, trophoblast development, and stem-cell-based embryo models

Key words

Program affiliation
Cancer Biology
Human and Statistical Genetics
Immunology
Molecular Genetics and Genomics

Research summary
Genomics of breast cancer etiology to identify targetable pathways

Key words
Genomics, biomarkers, metabolic imbalance, mammographic density, breast cancer, colorectal cancer, prevention,

Program affiliation
Immunology

Research summary
Receptor-mediated modulation of NK cell responses in vivo

Key words
innate immunity, NK cells, receptors, signal transduction, tolerance

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Molecular Genetics and Genomics
Immunology
Cancer Biology

Research summary
We want to understand how microbes interact with humans so that we can identify new strategies to improve health. Our research integrates 'skinomics', metagenomics and host-microbial genetics to address how microbes influence skin physiology.

Key words
microbiome, skin, dermatology, skin diseases, infection, skin cancer, wound healing, environmental exposures

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Cytokine-mediated tissue feedback loops that maintain homeostasis, and environmental factors that instigate inflammation and fibrosis.

Key words

Program affiliation
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Immunology
Cancer Biology

Research summary
The bone microenvironment for cancer and infection

Key words
bone biology, osteoclast, cancer, metastasis, osteoporosis, microenvironment, osteoblast, osteomyelitis, infection