Immunology
Aaron Ver Heul, MD, PhD
Assistant Professor
- Email: averheul@wustl.edu
Program affiliation
Immunology
Biochemistry Biophysics and Structural Biology
Neurosciences
Research summary
We work to improve human health by understanding allergies and itch. We tackle problems in a variety of ways from leveraging clinical samples to mouse models to molecular and biochemical assays.
Key words
itch, neuroimmunology, immunology, neuroscience, allergy, inflammation, mast cell
James Walsh, MD, PhD
Assistant Professor
- Email: walsh.j@wustl.edu
Program affiliation
Immunology
Neurosciences
Molecular Cell Biology
Research summary
The Walsh lab is interested in how the immune system is involved in both normal and pathological processes in the eye, exploring the contribution of both local immune cells and systemic immunity on ocular functioning.
Key words
Autoimmunity, CD4 T cell biology, Uveitis, CNS border immunology, Translational Research
Xiaoxiao Wan, MD, PhD
Assistant Professor
- Email: wanx@wustl.edu
Program affiliation
Immunology
Research summary
Pathogenesis and therapeutics in tissue-specific autoimmunity
Key words
Autoimmunity Neoantigens Tolerance Diabetes T cells Dendritic cells Macrophages
David Wang, PhD
Professor
- Email: davewang@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Computational and Systems Biology
Plant and Microbial Biosciences
Research summary
Discovery and Characterization of Novel Viruses
Key words
microbial pathogenesis, functional genomics, virology, genome analysis, computational biology
Jeffrey Ward, MD, PhD
Assistant Professor
- Email: jward2@wustl.edu
Program affiliation
Cancer Biology
Immunology
Research summary
Identification of tumor specific mutant antigens recognized by the immune system as foreign that serve as the target of a T-cell response against tumors
Key words
Max Wattenberg, MD
Assistant Professor
- Email: wattenberg@wustl.edu
Program affiliation
Cancer Biology
Immunology
Research summary
We are focused on exploiting features of the tumor microenvironment for cancer therapy. Specifically, we study stromal - tumor cell interactions in pancreatic cancer with the goal of defining clinically relevant cancer biology.
Key words
pancreatic cancer, immunotherapy, myeloid cells, tumor microenvironment, CRISPR screening
Sean Whelan, PhD
Marvin A. Brennecke Distinguished Professor and Head of the Department of Molecular Microbiology
- Email: spjwhelan@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Cell Biology
Research summary
The Whelan laboratory studies the biology of negative-strand (NS) RNA viruses, divided between two major areas of focus: viral gene expression and viral-host cell interactions.
Key words
Gregory Wu, MD, PhD
Associate Professor
- Email: gfwu@wustl.edu
Program affiliation
Immunology
Neurosciences
Research summary
Inflammation and autoimmunity of the central nervous system
Key words
antigen presentation, dendritic cells, B cells, immunology, intravital microscopy, multiple sclerosis, neurobiology
Meng Wu, PhD
Assistant Professor
- Email: mengwu@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
We investigate the interplay among the microbiota, stromal cells, and the immune system through the integration of microbiology and immunology with systems biology.
Key words
Microbiota, Microbiome, Immune system, Stromal cells, Vaccines, Germinal Centers
Kristine Wylie, PhD
Associate Professor
- Email: kwylie@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Host-microbe dynamics during pregnancy
Key words
virome, microbiome, pregnancy, papillomavirus, herpesvirus