Molecular Cell Biology
Jason Held, PhD
Assistant Professor
- Email: jheld@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
Redox biochemistry in cell signaling and disease, Proteomics
Key words
proteomics, post-translational modification, cysteine, redox, mass spectrometry, oxidation
Keith Hengen, PhD
Associate Professor
- Email: khengen@wustl.edu
Program affiliation
Neurosciences
Computational and Systems Biology
Molecular Cell Biology
Research summary
We take a "big data" approach to understanding the self-organization of neurons and networks in behaving animals.
Key words
Homeostatic plasticity, behavior, neurodegeneration, self-organization, emergence, learning, computational, computation, modeling
Andreas Herrlich, MD, PhD
Associate Professor
- Email: aherrlich@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
We aim to identify cellular and molecular mechanisms in the novel and rapidly expanding field of interorgan crosstalk in health and disease.
Key words
Erik Herzog, PhD
Viktor Hamburger Distinguished Professor
- Email: herzog@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biomedical Informatics and Data Science
Research summary
Molecular, cellular and circuit analysis of circadian rhythms in mammals
Key words
neurobiology, behavior, imaging, circadian rhythm, glia, brain cancer, potassium channels, neuropeptides, astrocytes, glioblastoma, cancer, developmental biology, computational modeling
Angela Hirbe, MD, PhD
Associate Professor
- Email: hirbea@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.
Key words
sarcoma, metastasis, genomics, cell signalling, NF1, MPNST
Alex Holehouse, PhD
Associate Professor
- Email: alex.holehouse@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Cell Biology
Plant and Microbial Biosciences
Research summary
Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
Key words
Disordered proteins, IDPs, IDRs, phase transitions, emergence, deep learning, AI, bird-themed software packages
David Holtzman, MD
Andrew B. and Gretchen P. Jones Professor
- Email: holtzman@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Research summary
Cellular and Molecular studies of Alzheimer’s disease
Key words
amyloid, tau, antibodies, apolipoprotein E, Alzheimer’s disease, neurodegeneration, neurobiology
Michael Holtzman, MD
Selma and Herman Seldin Professor
- Email: mjholtzman@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Research summary
New drugs for post-viral and related types of disease
Key words
drug discovery, innate immunity, epithelial stem cells, viruses, respiratory airway disease
Amjad Horani, MD
Associate Professor
- Email: horani_a@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Our lab studies airway and motile cilia biology and investigates the effects of mutations on cilia function
Key words
cilia, PCD, airway, lung
Paul Hruz, PhD, MD
Associate Professor
- Email: hruz_p@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance
Key words
protein structure, glucose transport, diabetes, AIDS, HIV therapy, membrane protein, structural biology, heart, affinity labeling, drug design