Molecular Cell Biology

Program affiliation
Molecular Cell Biology

Research summary
Aspects of sexual reproduction that involve membrane excitability and control of membrane voltage in spermatozoa, which are essential for the sperm to fertilize the egg

Key words
male fertility, ion channels, sperm physiology,

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
My laboratory uses genetics, cell biology and systems biology approaches to study how the cell regulates its metabolic programs and how dysfunctions in these programs lead to neurological disease

Key words

Program affiliation
Molecular Cell Biology
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Interactions between the nervous system and the skeleton

Key words
bone, diabetes, nerve, neuropathy, neuroskeletal biology, obesity, metabolism, adipose tissue, adipocyte, high-resolution imaging, advanced quantification, RNAseq, regeneration, healing

Program affiliation
Molecular Cell Biology

Research summary
Receptor-mediated protein targeting and protein degradation

Key words
proteins, receptor, endocytosis, metabolism

Program affiliation
Cancer Biology
Molecular Cell Biology

Research summary
Studying cancer therapy resistance mechanisms in humans and preclinical models

Key words
Tumor metabolism, glycolysis, glutaminolysis, imaging, microenvironment, HPV, immunology, radiation therapy

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
Understanding the mechanisms for degeneration and regeneration of soft tissues of the musculoskeletal system, including the intervertebral disc, articular cartilage, and meniscus

Key words

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
Molecular mechanisms and therapeutic potential of novel cancer targets

Key words
cancer, genome stability, targeted therapy, proteostasis, autophagy, DNA replication stress, DNA damage response, phosphorylation

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
We use zebrafish as a model for human hearing and balance with the goal of protecting and repairing inner ears from damage.

Key words
zebrafish, sensory neuroscience, hearing, balance, synaptic physiology, regeneration

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Focused on injury, repair, and regeneration of musculoskeletal tissues with the goal to understand the progenitor cell population, signals, and role of inflammation on tissue injury and regeneration at the cellular and molecular level

Key words

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Immunology
Neurosciences

Research summary
My research program integrates cardiovascular physiology, stem cell biology, developmental biology, functional genomics, and cardio-oncology to investigate molecular mechanisms of congenital and acquired cardiovascular diseases. My laboratory specializes in developing innovative protocols for generating authentic cardiovascular cell types from human induced pluripotent stem cells (iPSCs), advancing cardiovascular precision medicine. We aim to bridge basic science and clinical translation through disease modeling, therapeutic target identification, and adverse outcome prevention.

Key words
iPSC, CRISPR, organoid, cardiovascular, precision medicine, cardio-oncology