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Melissa Mavers, MD,PhD

Assistant Professor

Program affiliation
Immunology
Molecular Cell Biology
Cancer Biology

Research summary
Harnessing immune cells to prevent acute graft-versus-host disease

Key words
innate lymphocytes, graft-versus-host disease, cell therapies, cancer

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Gabriel Mbalaviele, PhD

Professor

Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Role of inflammasomes in disease

Key words
Inflammation, Inflammasomes, Skeleton, Cytokines

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Jordan McCall, PhD

Associate Professor

Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding the neural mechanisms underlying emotional dysregulation in the contexts of stress, chronic pain, and addiction

Key words

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Helen McNeill, PhD

Professor and BJC Investigator

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Cancer Biology
Molecular Genetics and Genomics

Research summary
Coordinating cell proliferation and cell organization in organ development

Key words

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Steven Mennerick, PhD

Professor

Program affiliation
Neurosciences
Molecular Cell Biology

Research summary
Physiology of glutamate and GABA neurotransmission in the CNS

Key words
neurobiology, synapse biology, receptor, ion channel, glutamate transmission, GABA transmission

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Jeffrey Milbrandt, MD, PhD

James S. McDonnell Professor

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
Axonal degeneration, regulation of myelination, neuronal energetics and mitochondrial function in neuropathy and neurodegenerative disease

Key words
functional genomics, metabolism, mitochondria, diabetic neuropathy, neurodegeneration, transcriptional networks, Alzheimer’s disease, Schwann cell

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Timothy Miller, MD, PhD

David Clayson Professor

Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Mechanisms of neurodegeneration and targeted therapies for neurodegenerative diseases

Key words
ALS (amyotrophic lateral sclerosis), SOD1, TDP-43, C9ORF72, miRNA, Tau, Dementia, Neurodegeneration, Antisense oligonucleotides

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Jeffrey Millman, PhD

Professor

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
Differentiation to and maturation of pancreatic insulin-producing β cells from human pluripotent stem cells capable of rapidly reversing diabetes

Key words
stem cell biology, regeneration, developmental biology, microscopy, single-cell RNA-sequencing, differentiation, tissue engineering, diabetes, organoids, transplantation, therapy

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S. Celeste Morley, MD, PhD

Associate Professor

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology

Research summary
Cell biology of the immune system -- understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection

Key words
actin cytoskeleton, L-plastin, T cell, B cell, lymphocyte motility, pneumococcal pneumonia,

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Jose Moron-Concepcion, PhD

Professor

Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Elucidating the molecular mechanisms underlying opiate dependence

Key words
opioids, addiction, pain, molecular mechanisms, animal models