Molecular Cell Biology
Jennifer Philips, MD, PhD
Theodore and Bertha Bryan Professor
- Email: philips.j.a@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Cell Biology
Research summary
Immune Evasion by Mycobacterium tuberculosis
Key words
tuberculosis, host-pathogen interactions, innate immunity, autophagy, lipid metabolism, phagosome maturation, antigen presentation, macrophage
Jennifer Phillips-Cremins, PhD
BJC Investigator and James S. McDonnell Professor
- Email: jennifer.cremins@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Neurosciences
Computational and Systems Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
The Cremins lab integrates molecular and computational biology to elucidate how the genome’s structure-function relationship influences synaptic plasticity and neurophysiology during memory encoding and consolidation and how this goes awry in intractable neurological disorders.
Key words
chromatin, neuroepigenetics, 3D genome, synaptic plasticity, Alzheimer's, repeat expansion disorders, chromatin-synapse communication, neural connectome, organoids
Marco Pignatelli, MD
Assistant Professor
- Email: marco.pignatelli@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Research summary
Understanding the synaptic mechanisms by which emotional experiences lead to maladaptive plasticity and the impact of neurotherapeutic drugs on those maladaptive synaptic neuroadaptations
Key words
synaptic plasticity, Optogenetics, cell-type specific pharmacology, patch clamp electrophysiology, rapid-acting antidepressants, motivated behavior, drug addiction and affective disorders
Linda Pike, PhD
Professor
- Email: pike@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
EGF receptor-mediated cell signaling and the control of cell growth
Key words
signal transduction, cell signaling, cancer, EGF receptor
David Piston, PhD
Edward Mallinckrodt, Jr. Professor and Head of the Department of Cell Biology & Physiology
- Email: piston@wustl.edu
Program affiliation
Molecular Cell Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
Studies of the Molecular Pathways of Islet Hormone Secretion
Key words
Diabetes, Biophysics, Systems Biology, Computational Biology, Hyperspectral Imaging, Glucagon
Elizabeth Ann Pollina, PhD
Assistant Professor
- Email: pollina@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Molecular Mechanisms of Nervous System Longevity and Rejuvenation
Key words
epigenetics, nervous system, DNA repair, aging, rejuvenation
Sumanth Prabhu, MD
Tobias & Hortense Lewin Distinguished Professor of Cardiovascular Disease
- Email: prabhu@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Cell Biology
Research summary
Key words
Amynah Pradhan, PhD
Associate Professor
- Email: amynah@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Research summary
My lab studies the molecular mechanisms of migraine chronicity, with an emphasis on opioid receptors
Key words
Opioids, pain, migraine, mouse models, neuroplasticity, addiction
Rithwick Rajagopal, MD, PhD
Assistant Professor
- Email: rajagopalr@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Regulation of neural lipid and glucose metabolism in diseases of the retina
Key words
Gwendalyn Randolph, PhD
Emil R. Unanue Distinguished Professor
- Email: gjrandolph@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
We focus on inter-organ communication and the transit of cells and molecules out of tissues in healthy and disease states
Key words
lymphatic vessels, lymph nodes, IBD, monocytes, macrophages, high-density lipoprotein, peritoneal tumor metastasis, peritoneal macrophages