Molecular Genetics and Genomics
Tim Schedl, PhD
Professor
- Email: ts@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Research summary
Control of germline stem cells and meiotic development in C. elegans
Key words
germ cells, C. elegans, genetics, development, functional genomics
Laura Schuettpelz, MD, PhD
Professor
- Email: schuettpelz_l@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Immunology
Molecular Genetics and Genomics
Research summary
Regulation of hematopoietic stem cells (HSCs) by inflammation
Key words
Drew Schwartz, MD, PhD
Assistant Professor
- Email: Schwartzd@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Pediatric gut microbiome and immune disruption in serious bacterial infections
Key words
Microbiome, sepsis, bacteremia, infectious diseases, immune response, pediatrics
Clay Semenkovich, MD
Irene E. and Michael M. Karl Professor
- Email: csemenko@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
Molecular and cell biology of atherosclerosis and diabetes
Key words
aging, atherosclerosis, diabetes, lipids, obesity
Jieya Shao, PhD
Associate Professor
- Email: shao.j@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Research summary
Molecular mechanisms and therapeutic potential of novel cancer targets
Key words
cancer, genome stability, targeted therapy, proteostasis, autophagy, DNA replication stress, DNA damage response, phosphorylation
Paul Shaw, PhD
Associate Professor
- Email: shawp@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Research summary
Molecular/genetic analysis of sleep function
Key words
neurobiology, genetics, sleep, gene expression, memory, plasticity, Alzheimer`s disease,
Jie Shen, PhD
Associate Professor
- Email: shen.j@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Focused on injury, repair, and regeneration of musculoskeletal tissues with the goal to understand the progenitor cell population, signals, and role of inflammation on tissue injury and regeneration at the cellular and molecular level
Key words
L. David Sibley, PhD
Professor
- Email: sibley@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Research summary
Cellular and molecular basis of intracellular parasitism by protozoan parasites
Key words
cell-signaling, kinases, transcription, chromatin, pathogenesis, genetics, genomics, chemical biology, innate immunity
Jessica Silva-Fisher, PhD
Assistant Professor
- Email: silvajm@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Long non-coding RNAs and RNA modifications in cancer metastasis and relapse
Key words
Cancer metastasis, multiple myeloma, breast cancer, long non-coding RNAs, RNA modifications, genomics
Gary Silverman, MD, PhD
Harriet B Spoehrer Professor and Head of the Department of Pediatrics
- Email: gsilverman@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
The cellular response to life threatening human diseases.
Key words
serpins, cell death, lysosomes, necrotizing enterocolitis, C. elegans, proteases, protein misfolding, alpha-1 antitrypsin deficiency, drug discovery