Programs
Roberto Civitelli, MD
Professor
- Email: civitellir@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Cancer Biology
Research summary
Connexins, cadherins in bone cell interactions with cancer and energy metabolism
Key words
bone biology, cell adhesion, signal transduction, gap junctions, cadherin
Brian Clark, PhD
Assistant Professor
- Email: brian.s.clark@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics
Research summary
Genetic and epigenetic control of retinal development and retinal cell fate specification
Key words
Regina Clemens, MD, PhD
Associate Professor
- Email: clemensra@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Research summary
The mechanisms regulating calcium-dependent neutrophil activation
Key words
Barak Cohen, PhD
Alvin Goldfarb Distinguished Professor of Computational Biology
- Email: cohen@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Genomic analyses of regulatory networks, Non-coding disease variants
Key words
Genomics, Genetic Variation, High-Throughput Technologies, Single-Cell Regulatory Genomics, Computational Biology
Graham Colditz, MD, DrPH
Niess-Gain Professor
- Email: colditzg@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Molecular Genetics and Genomics
Research summary
Causes and prevention of breast cancer, premalignant lesions, risk stratification
Key words
breast cancer, cancer, genetic epidemiology, hormones, obesity, obesity and malnutrition
John Cooper, MD, PhD
Professor
Program affiliation
General
Research summary
Molecular mechanisms of cell motility and cytoskeleton assembly
Key words
cell motility, cytoskeleton, actin, intermediate filament, microtubules, septin, cell migration
Jonathan Cooper, PhD
Professor
- Email: cooperjd@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology
Research summary
Disease mechanisms and treatments for inherited childhood neurodegeneration
Key words
Batten Disease, Neuronal Ceroid Lipofuscinosis, NCL, Lysosomal Storage Disease, pathogenesis, pre-clinical therapies, enzyme replacement, gene therapy
Megan Cooper, MD, PhD
Anthony R. French, MD, PhD, Professor
- Email: cooper_m@wustl.edu
Program affiliation
Immunology
Human and Statistical Genetics
Research summary
The Cooper laboratory is focused on investigating the molecular and immunologic basis of inborn errors of immunity. We are particularly interested in understanding novel genetic causes of these diseases in children with immune dysregulation syndromes.
Key words
inborn errors of immunity, genetics, primary immunodeficiency STAT3, TLR8, Pediatrics
Bryan Copits, PhD
Assistant Professor
- Email: bcopits@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
We study how different types of neurons encoding somatosensory modalities are assembled into functional circuits in both humans and model organisms.
Key words
pain, optogenetics, imaging, electrophysiology
Joseph Corbo, MD, PhD
Professor
- Email: jcorbo@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Neurosciences
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology
Research summary
(1) transcriptional networks in the retina; (2) the mechanistic basis of color vision; (3) the cis-regulatory basis of human uniqueness and neuropsychiatric disease
Key words
neurobiology, genomics, transcriptional networks, systems biology, photoreceptors, brain, neuropsychiatric disease, disease, cis-regulation