Programs

Program affiliation
Biomedical Informatics and Data Science
Cancer Biology

Research summary
Development of novel statistical methods for precision medicine

Key words
Biostatistics; Image analysis; Dynamic risk prediction; Multistate models

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Human and Statistical Genetics

Research summary
We use human genetic, functional genomic, and bioinformatic approaches to understand the consequence of genetic variants underlying diseases

Key words
Functional genomics, bioinformatics, human genetics, data science, rare diseases, structural variation

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Cancer Biology

Research summary
I am interested in precursor conditions or metaplasias in the stomach and esophagus (i.e Barrett’s esophagus) as these lesions are key to understanding the formation of gastroesophageal adenocarcinomas.

Key words
Intestinal metaplasia, gastroesophageal cancer, Barrett's esophagus, GI development, Organoids

Program affiliation
Immunology
Cancer Biology

Research summary
Novel immunotherapeutic strategies to treat solid tumors

Key words

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Immunology

Research summary
Molecular mechanisms of skeletal and cardiac muscle development and disease

Key words
muscle, congenital disease, organogenesis, gene discovery

Program affiliation
General

Research summary
Using statistical and population genomics approaches to better understand the genetic architecture of complex traits, with a focus on substance use disorders.

Key words
behavioral genetics; genomics; statistical genetics; evolutionary genetics; population genetics; substance use disorders; cannabis; schizophrenia; complex traits; psychiatric disorders

Program affiliation
General

Research summary
Developing geometric algorithms for interpreting protein structures from low-resolution density maps produced by cryo-electron microscopy and X-ray crystallography

Key words
molecular imaging, geometric algorithms, anatomical modeling, computer graphics, biomedicine

Program affiliation
General

Research summary

Key words

Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology

Research summary
Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose

Key words
Hematopoietic stem cells, Multipotent progenitors, Cell fate decision, Lineage specification, Stem cell biology, Cancer (myeloid leukemia), Aging

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Genetics and Genomics

Research summary

Key words