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Heather A. Lawson, PhD

Assistant Professor

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics

Research summary
Integration of whole-genome sequence with phenotypic data to understand parent-of-origin genetic effects and gene-by-environment interactions

Key words
Epigenetics, gene regulation, parent-of-origin effects, gene-by-environment interactions, pleiotropy, systems biology, metabolism, evolution

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Aaron Y. Lee, MD, MSCI

Arthur W. Stickle Distinguished Professor and Chair of the Department of Ophthalmology and Visual Sciences

Program affiliation
Biomedical Informatics and Data Science

Research summary

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Cecilia Lee, MD

Jane Hardesty Poole Endowed Professor

Program affiliation
Biomedical Informatics and Data Science
Neurosciences

Research summary
The Lee Laboratory develops computational approaches to advance precision medicine through retinal imaging, artificial intelligence, and multimodal biomedical data. Our research integrates ophthalmic imaging, clinical phenotypes, wearable sensors, electronic health records, and multi-omics to discover noninvasive biomarkers of systemic diseases, including diabetes, Alzheimer's disease, and cardiovascular disease. Through large-scale collaborative studies such as Eye ACT, AI-READI, and the Framingham Heart Study Eye Project, we build open, AI-ready resources that accelerate scientific discovery and improve patient care.

Key words
Big Data, AI, Ophthalmology, Clinical Epidemiology, Alzheimer's, Oculomics

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Janet Lee, MD

Selma and Herman Seldin Distinguished Professor of Medicine

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary

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Jin-Moo Lee, MD, PhD

Andrew B. And Gretchen P. Jones Professor and Head of the Department of Neurology

Program affiliation
Neurosciences
Computational and Systems Biology

Research summary
Pathogenesis of amyloid fibrils and amyloid plaques in AD mouse models

Key words
brain ischemia, stroke recovery, Alzheimer’s disease, amyloid

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Deborah J. Lenschow, MD, PhD

John S. Daniels Professor

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases

Key words
host-pathogen interactions, immunology, innate immunity, interferons, pathogenesis, virology, autoimmune disease, lupus

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Michele LeRoux, PhD

Assistant Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
We study how bacterial defend themselves from their viral predators, bacteriophage.

Key words
bacteria, phage, bacteriophage, virus

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Daisy W. Leung, PhD

Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology

Research summary
Defining molecular mechanisms at the host-pathogen interface

Key words

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Eric Leuthardt, MD

Professor

Program affiliation
Neurosciences

Research summary

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Petra Levin, PhD

George William and Irene Koechig Freiberg Professor

Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology

Research summary
Bacterial growth and antibiotic susceptibility

Key words
Bacterial, growth size, antibiotics, tolerance, antibiotic resistance, systems biology, cytoskeleton, biochemistry, microbiology, microscopy