Programs
Heather A. Lawson, PhD
Assistant Professor
- Email: lawson@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Research summary
Integration of whole-genome sequence with phenotypic data to understand parent-of-origin genetic effects and gene-by-environment interactions
Key words
Epigenetics, gene regulation, parent-of-origin effects, gene-by-environment interactions, pleiotropy, systems biology, metabolism, evolution
Aaron Y. Lee, MD, MSCI
Arthur W. Stickle Distinguished Professor and Chair of the Department of Ophthalmology and Visual Sciences
- Email: leeay@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Research summary
Key words
Cecilia Lee, MD
Jane Hardesty Poole Endowed Professor
- Email: cslee@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Neurosciences
Research summary
The Lee Laboratory develops computational approaches to advance precision medicine through retinal imaging, artificial intelligence, and multimodal biomedical data. Our research integrates ophthalmic imaging, clinical phenotypes, wearable sensors, electronic health records, and multi-omics to discover noninvasive biomarkers of systemic diseases, including diabetes, Alzheimer's disease, and cardiovascular disease. Through large-scale collaborative studies such as Eye ACT, AI-READI, and the Framingham Heart Study Eye Project, we build open, AI-ready resources that accelerate scientific discovery and improve patient care.
Key words
Big Data, AI, Ophthalmology, Clinical Epidemiology, Alzheimer's, Oculomics
Jin-Moo Lee, MD, PhD
Andrew B. And Gretchen P. Jones Professor and Head of the Department of Neurology
- Email: leejm@wustl.edu
Program affiliation
Neurosciences
Computational and Systems Biology
Research summary
Pathogenesis of amyloid fibrils and amyloid plaques in AD mouse models
Key words
brain ischemia, stroke recovery, Alzheimer’s disease, amyloid
Deborah J. Lenschow, MD, PhD
John S. Daniels Professor
- Email: dlenschow@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases
Key words
host-pathogen interactions, immunology, innate immunity, interferons, pathogenesis, virology, autoimmune disease, lupus
Michele LeRoux, PhD
Assistant Professor
- Email: mleroux@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
We study how bacterial defend themselves from their viral predators, bacteriophage.
Key words
bacteria, phage, bacteriophage, virus
Daisy W. Leung, PhD
Professor
- Email: dwleung@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Research summary
Defining molecular mechanisms at the host-pathogen interface
Key words
Eric Leuthardt, MD
Professor
- Email: leuthardte@wustl.edu
Program affiliation
Neurosciences
Research summary
Key words
Petra Levin, PhD
George William and Irene Koechig Freiberg Professor
- Email: plevin@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Bacterial growth and antibiotic susceptibility
Key words
Bacterial, growth size, antibiotics, tolerance, antibiotic resistance, systems biology, cytoskeleton, biochemistry, microbiology, microscopy