Programs

Bhuvic Patel, MD
Assistant Professor
- Email: bhuvic.patel@wustl.edu
Program affiliation
Neurosciences
Cancer Biology
Computational and Systems Biology
Research summary
Our lab employs cutting-edge molecular biology techniques to investigate the genetic, epigenetic, and cellular alterations driving the initiation, progression, and therapeutic resistance of brain tumors.
Key words
brain tumors, systems biology, genetics, neurosurgery, neurooncology

Amit Pathak, PhD
Associate Professor
- Email: pathaka@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
We combine experimental measurements and computational modeling to understand how single and grouped respond to physical heterogeneities present in their extracellular microenvironments.
Key words
Mechanobiology; tumor invasion; cell migration; epithelial-mesenchymal transition; cell-matrix interaction; cytoskeleton;

Gary Patti, PhD
Michael and Tana Powell Professor
- Email: gjpattij@wustl.edu
Program affiliation
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
To understand the metabolic crosstalk between cells and tissues in disease models such as cancer by using isotopes and metabolomics
Key words
metabolism, metabolomics, mass spectrometry, bioinformatics, imaging, cancer, tumor microenvironment, isotope tracing

Slavica Pavlovic Djuranovic, PhD
Assistant Professor
- Email: spavlov@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
Identifying new targets and possible therapies to treat malaria
Key words
malaria, mRNA surveillance, drug discovery

Philip Payne, PhD, FACMI
Janet and Bernard Becker Professor
- Email: prpayne@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Translational Bioinformatics, Clinical Research Informatics
Key words
Biomedical Informatics, Data Science, Data Analytics, Clinical Research, Translational Research

Jacqueline Payton, MD, PhD
Associate Professor
- Email: jpayton@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Biomedical Informatics and Data Science
Molecular Microbiology and Microbial Pathogenesis
Research summary
Epigenomic aberrations in B cell lymphomas and their impact on gene regulation
Key words
epigenomics, cancer, lymphoma, histone, informatics, genomics, gene regulation

Rachel Penczykowski, PhD
Assistant Professor
- Email: rpenczykowski@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences
Research summary
The ecology and evolution of infectious diseases, with a focus on wild populations of herbaceous plant hosts and their powdery mildew pathogens.
Key words
host-parasite interactions, disease ecology, plant pathogens, urban ecology, climate change

Guangyong Peng, MD, PhD
Professor
- Email: pengg@wustl.edu
Program affiliation
Immunology
Cancer Biology
Neurosciences
Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.
Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy

Susan Perlman, PhD
Associate Professor
- Email: perlmansusan@wustl.edu
Program affiliation
Neurosciences
Research summary
Key words

David Perlmutter, MD
Spencer T. and Ann W. Olin Distinguished Professor
- Email: perlmutterd@wustl.edu
Program affiliation
Molecular Cell Biology
Immunology
Molecular Genetics and Genomics
Research summary
Pathobiology of liver disease from accumulation and proteotoxicity of misfolded proteins in α1-antitrypsin deficiency; role of autophagy in biology and treatment of disorders caused by misfolded proteins
Key words
α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs