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Jay W. Ponder, PhD

Associate Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology

Research summary
Computational chemistry, protein engineering, theoretical protein structure and folding

Key words
molecular modeling, protein structure, computational chemistry, molecular dynamics simulation, protein engineering

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Cyril Pottier, PhD

Assistant Professor

Program affiliation
General

Research summary

Key words

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Sumanth Prabhu, MD

Tobias & Hortense Lewin Distinguished Professor of Cardiovascular Disease

Program affiliation
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Cell Biology

Research summary

Key words

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Amynah Pradhan, PhD

Associate Professor

Program affiliation
Neurosciences
Molecular Cell Biology

Research summary
My lab studies the molecular mechanisms of migraine chronicity, with an emphasis on opioid receptors

Key words
Opioids, pain, migraine, mouse models, neuroplasticity, addiction

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Michael A. Province, PhD

Professor

Program affiliation
Human and Statistical Genetics
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
Mathematical development, evaluation, and application of new, and state-of-the-art statistical genetics methodology for complex traits and diseases, with a fondness for run-on sentences.

Key words
biostatistics, genetic epidemiology, human genetics, mathematical modeling, statistical genetics, systems biology

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John R. Pruett, Jr., MD, PhD

Professor

Program affiliation
Neurosciences
Biomedical Informatics and Data Science

Research summary
The neuroscience of ASD, social cognition and comparative cognition

Key words
fcMRI, fMRI, infant, autism, face perception, visual attention, psychophysics, social cognition, comparative cognition

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Sid Puram, MD, PhD

Lindburg Professor and Chair of the Department of Otolaryngology

Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Computational and Systems Biology
Immunology
Developmental Regenerative and Stem Cell Biology

Research summary
Understanding the role of tumor heterogeneity in cancer biology using single cell and spatial techniques, with an emphasis on how tumor subpopulations (malignant, stromal, and immune cells) drive cancer development, growth, metastasis, and treatment resistance. We are particularly focused on how to translate these insights into new diagnostics and novel therapeutics.

Key words
tumor heterogeneity; single cell; spatial transcriptomics; head and neck cancer; signaling

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David Queller, PhD

Spencer T. Olin Professor

Program affiliation
General

Research summary
The evolution of sociality, cooperation, and cheating in a eukaryotic microbe, using experimental evolution, genomics, and other approaches

Key words
social interactions, evolution, microbiology, social amoebae, kin selection, moleuclar evolution, multicellularity, development, genomics

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Marcus E. Raichle, MD

Professor

Program affiliation
Neurosciences

Research summary
Functional brain imaging with positron emission tomography and magnetic resonance

Key words
imaging, behavior, cognition, fMRI, PET

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Rithwick Rajagopal, MD, PhD

Assistant Professor

Program affiliation
Molecular Cell Biology

Research summary
Regulation of neural lipid and glucose metabolism in diseases of the retina

Key words