Programs
David Rosen, MD, PhD
Associate Professor
- Email: rosend@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
Pathogenesis and host response to Klebsiella pneumoniae infections
Key words
Klebsiella pneumoniae, Antibiotic Resistance, Pneumonia, Urinary Tract Infection, Neonatal Sepsis, Virulence Factors, Adaptive Immunity
Ronald C. Rubenstein, MD, PhD
Robert C. Strunk Endowed Chair for Lung and Respiratory Research Professor
- Email: rubenstein@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding the mechanisms by which a novel chaperone of the Endoplasmic Reticulum, ERp29, regulates the biogenesis of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), the Epithelial Sodium Channel (ENaC), and other proteins related to pediatric pulmonary diseases
Key words
Cystic Fibrosis, Chaperone, Endoplasmic Reticulum, CFTR, ENaC/Epithelial Sodium Channel, Epithelia, Insulin, Trafficking, Biogenesis
Joshua B. Rubin, MD, PhD
Professor
- Email: Rubin_J@wustl.edu
Program affiliation
General
Research summary
Molecular mechanisms in pediatric brain tumorigenesis
Key words
tumor biology, signal transduction, stem cells, neural development, sexual dimorphism, circadaian rhythm, chemokines, cAMP
David A. Rudnick, MD, PhD
Associate Professor
- Email: rudnick_d@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Research summary
Molecular mechanisms of liver injury and regeneration
Key words
liver; regeneration; alpha 1 antitrypsin deficiency; liver disease; aflatoxin; acute liver failure; cell cycle; mouse models; epigenetics; metabolism
Jai S. Rudra, PhD
Associate Professor
- Email: srudra22@wustl.edu
Program affiliation
General
Research summary
Development of nano-scale biomaterials for engaging the immune system to induce protective antibody and cell-mediated immune responses against diseases
Key words
John H. Russell, PhD
Professor
- Email: jrussell@wustl.edu
Program affiliation
General
Research summary
CNS/lymphocyte interactions regulating inflammation and pathogenesis in a mouse model of multiple sclerosis
Key words
apoptosis, autoimmunity, imaging, inflammation, multiple sclerosis
Mark A. Rutherford, PhD
Associate Professor
- Email: rutherfordmark@wustl.edu
Program affiliation
Neurosciences
Research summary
Cellular mechanisms underlying our systems of sound and balance encoding in development, in maturity, and in pathology of hearing or vestibular function
Key words
cochlea, neurodegeneration, synapse, excitotoxicity, encoding sound
Philip Ruzycki, PhD
Assistant Professor
- Email: p.ruzycki@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Biomedical Informatics and Data Science
Computational and Systems Biology
Research summary
Key words
retina development, epigenetics, histones
Nancy L. Saccone, PhD
Associate Professor
- Email: nlims@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Statistical genetics, complex human diseases, analysis methods
Key words
genetics, substance dependence, addiction, human disease gene mapping, association studies, linkage and linkage disequilibrium
Jose B. Saenz, MD, PhD
Assistant Professor
- Email: saenzj@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Gastric epithelial responses to acute and chronic gastric injury
Key words
double-stranded RNA, host response, Helicobacter pylori