Programs
L. David Sibley, PhD
Professor
- Email: sibley@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Research summary
Cellular and molecular basis of intracellular parasitism by protozoan parasites
Key words
cell-signaling, kinases, transcription, chromatin, pathogenesis, genetics, genomics, chemical biology, innate immunity
Jonathan Silva, PhD
Associate Professor
- Email: jonsilva@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Biomedical Informatics and Data Science
Research summary
Engineering to help cardiac arrhythmia patients feel better and live longer.
Key words
Bioelectricity, Arrhythmias, Modeling, Molecular Imaging, Electrophysiology, Induced Pluripotent Stem Cells
Matthew Silva, PhD
Professor
- Email: silvam@wustl.edu
Program affiliation
Molecular Cell Biology
Human and Statistical Genetics
Research summary
Skeletal mechanobiology; bone strength; osteoporosis; bone fracture, repair & regeneration
Key words
bone mechanics, bone biology, injury, mechanotransduction, mouse models, osteoporosis
Jessica Silva-Fisher, PhD
Assistant Professor
- Email: silvajm@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Long non-coding RNAs and RNA modifications in cancer metastasis and relapse
Key words
Cancer metastasis, multiple myeloma, breast cancer, long non-coding RNAs, RNA modifications, genomics
Gary Silverman, MD, PhD
Harriet B Spoehrer Professor and Head of the Department of Pediatrics
- Email: gsilverman@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
The cellular response to life threatening human diseases.
Key words
serpins, cell death, lysosomes, necrotizing enterocolitis, C. elegans, proteases, protein misfolding, alpha-1 antitrypsin deficiency, drug discovery
Srikanth Singamaneni, PhD
Associate Professor
- Email: singamaneni@WUSTL.EDU
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Plasmonic biosensors and biomimetic sensors
Key words
biomimetic sensors, plasmonic biosensors, nanostructures, transduction platforms
Nathan Singh, MD, MS
Assistant Professor
- Email: nathan.singh@wustl.edu
Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding how synthetic antigen receptors direct T cell function and dysfunction in the treatment of blood cancers
Key words
CAR T cell therapy, immunotherapy for cancer, T cell signaling, T cell dysfunction, lineage decisions
James Skeath, PhD
Professor
- Email: jskeath@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences
Research summary
Genetic analysis of neural and muscular development in the Drosophila embryo
Key words
development, neurobiology, cell signaling
R. Keith Slotkin, PhD
Full Member and Principal Investigator
Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Research summary
Investigating how plant cells determine which fragments of DNA should be expressed (like genes), and which should be targeted for repression and not allowed to express
Key words
transposable element, epigenetics, DNA methylation, chromatin, transgene silencing
Christopher Smyser, MD
Professor
- Email: smyserc@wustl.edu
Program affiliation
Neurosciences
Research summary
Investigating the effects of prematurity and other modifiable clinical and environmental risk factors on neurodevelopmental outcomes in high-risk pediatric populations
Key words
Neurodevelopment; neonate; prematurity; psychopathology; brain injury; MRI; structural connectivity; functional connectivity